Post-operative Analgesia in Elective, Soft-tissue Hand Surgery



Status:Terminated
Conditions:Neurology, Orthopedic, Orthopedic
Therapuetic Areas:Neurology, Orthopedics / Podiatry
Healthy:No
Age Range:18 - Any
Updated:12/15/2018
Start Date:February 10, 2015
End Date:June 30, 2018

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Post-operative Analgesia in Elective, Soft-tissue Hand Surgery: A Randomized, Double Blind Comparison of Acetaminophen/Ibuprofen Versus Acetaminophen/Hydrocodone

The purpose of this research study is to find out which combination of pain medications
following surgery work the best and result in the fewest side effects.

This is a prospective, randomized, double-blind study comparing the efficacy of
acetaminophen/hydrocodone (AH) to acetaminophen/ibuprofen (AIBU) in providing adequate
post-operative pain relief in elective, soft tissue hand surgery patients.

Inclusion Criteria:

- Age greater than or equal to 18

- Male or Female (non-pregnant)

- Elective, soft tissue hand surgery indicated based on diagnosis made by either
clinical exam or diagnostic studies (ie nerve conduction study, EMG) or a combination
of the two (carpal tunnel release, trigger finger release, first dorsal compartment
release, ganglion cyst excision, second extensor compartment release)

- Subjects are capable of giving informed consent

Exclusion Criteria:

- Allergy to study medication

- Any pre-existing pain condition requiring analgesia

- Fibromyalgia

- Recent upper gastrointestinal bleeding

- Coagulopathy (primary or medication-related)

- Renal impairment

- Liver disease

- Pregnancy

- Patients who consent to the study but require unexpected admission, including those
requiring admission resulting from operative complications, will be excluded before
randomization
We found this trial at
1
site
500 University Dr
Hershey, Pennsylvania 17033
(717) 531-6955
Penn State Milton S. Hershey Medical Center Penn State Milton S. Hershey Medical Center, Penn...
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mi
from
Hershey, PA
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