Peak Cough Flow and Cough Clearance in Patients With Muscular Dystrophy
| Status: | Recruiting |
|---|---|
| Conditions: | Infectious Disease, Neurology, Neurology, Orthopedic |
| Therapuetic Areas: | Immunology / Infectious Diseases, Neurology, Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 6 - 21 |
| Updated: | 2/9/2019 |
| Start Date: | January 2014 |
| End Date: | January 2020 |
Pilot Study of Cough Peak Flow And Airway Clearance in Pediatric Patients With Neuromuscular Disease
This study is to determine whether physiologic measures (peak cough flow, measures of
respiratory muscle strength including MIP, MEP ,SNIP, and spirometry) can predict spontaneous
cough clearance (as measured by a nuclear medicine study) in children with neuromuscular
disease. It will also determine whether airway clearance is augmented by high frequency chest
wall oscillation.
respiratory muscle strength including MIP, MEP ,SNIP, and spirometry) can predict spontaneous
cough clearance (as measured by a nuclear medicine study) in children with neuromuscular
disease. It will also determine whether airway clearance is augmented by high frequency chest
wall oscillation.
Inclusion Criteria:
- Age 6-21; able to cooperate with study procedures
- Duchenne Muscular Dystrophy OR Becker Muscular Dystrophy
Exclusion Criteria:
- Need for mechanical ventilation during the day
- Recent (within 2 weeks) lower respiratory tract infection
We found this trial at
1
site
3414 Fifth Avenue
Pittsburgh, Pennsylvania 15213
Pittsburgh, Pennsylvania 15213
Principal Investigator: Daniel J. Weiner, MD
Phone: 412-692-5873
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