A Study of Lifestyle Intervention in Overweight or Obese Women With Early Stage Breast Cancer

- Primary endpoint: To examine the effects of a practical lifestyle intervention that can
be implemented by overweight or obese women (BMI greater or equal to 25) with early
stage breast cancer (I-III) on outcomes such as body weight and change in BMI over the
course of the study.

- Secondary endpoint: To assess the impact of such intervention on lipid profiles and
hemoglobin A1C. The study group will be compared with a historical control group of
patients with early stage breast cancer who are obese or overweight who were not given
the intervention

- Secondary endpoint: To examine whether an active intervention program will lead into
longstanding lifestyle modification in breast cancer patients with a BMI greater or
equal to 25.

Inclusion Criteria:

- DCIS

- Women with stage 0 - III breast cancer (histologic type ductal or lobular)

- BMI >=25

- Patients must have completed all chemotherapy

- Patients may be on hormonal therapy or radiation therapy

- Age >= 18 years old to 89 Years old

- Patient must be medically stable and without significant impairments that would
preclude following the proposed intervention regimen.

- Time of diagnosis: patients enrolled are within 1 month to 18 months post-diagnosis.

Exclusion Criteria:

- Metastatic breast cancer patients and patients with inoperable or active
loco-regional disease.

- Patients following alternative/complementary diets or taking high dose antioxidant
supplements.

- Patients with a physical/psychiatric impairment that would seriously impair their
physical mobility.

- Patients who are currently suffering from severe nausea, anorexia or other diseases
affecting health (e.g. arthritis and multiple sclerosis).

- Patients younger than 18 and older than 89 years.