Trevo® Retriever Registry Post Market Surveillance

Trevo Retriever Registry is a prospective, open-label, consecutive enrollment, multi-center,
international registry that may enroll a maximum of 2000 patients at up to 100 sites
worldwide. Revascularization status will be assessed at the end of the procedure using the
modified TICI (Thrombolysis in Cerebral Infarction)score. Additional data collection will
include:

1. Day 90 mRS assessment

2. Day 90 all cause mortality

3. Neurological deterioration at 24 hours post procedure, defined as a four or more point
increase in the NIHSS score from the baseline score

4. Rates of device and procedure related serious adverse events (AEs)

Inclusion Criteria:

- Subjects experiencing acute ischemic stroke who are eligible for restoration of blood
flow using any approved Trevo Retriever in the neurovasculature to remove thrombus

- Trevo Retriever is the initial mechanical neuro-thrombectomy device used to remove the
thrombus

- Signed Informed Consent obtained

- Subject willing to comply with the protocol follow-up requirements

- Anticipated life expectancy of at least 3 months

Exclusion Criteria:

- The subject is participating in another mechanical neuro-thrombectomy device trial or
any other clinical trial where the study procedure or treatment might confound the
study end point.