Detecting Lung Infections Through Vibration
| Status: | Completed |
|---|---|
| Conditions: | Infectious Disease |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 4/21/2016 |
| Start Date: | February 2014 |
| End Date: | December 2015 |
Feasibility and Optimization of High Frequency Oscillation (HFO) for Detection of Lung Infections
The purpose of this study is to test a lung air vibrator device for vibrating air inside the
lung. This exploratory diagnostic trial will test a novel and non-invasive means of
detecting lower airway infections using exhaled breath sample.
lung. This exploratory diagnostic trial will test a novel and non-invasive means of
detecting lower airway infections using exhaled breath sample.
This study has two phases. Once the subject has consented phase 1 will start by the subject
breathing air out of their lungs into the device. Next, the subject will simply breathe
through the mouthpiece with the machine turned on and take samples of exhaled air.
In phase 2, the subjects will breathe air out of their lungs into the device for 15 minutes.
Next, the subject will simply breathe through the mouthpiece with the machine turned on and
take samples of exhaled air for 15 minutes.
breathing air out of their lungs into the device. Next, the subject will simply breathe
through the mouthpiece with the machine turned on and take samples of exhaled air.
In phase 2, the subjects will breathe air out of their lungs into the device for 15 minutes.
Next, the subject will simply breathe through the mouthpiece with the machine turned on and
take samples of exhaled air for 15 minutes.
Inclusion Criteria:
- Age 18-50
Exclusion Criteria:
- History of major respiratory compromise (except cystic fibrosis if included within
cystic fibrosis cohort)
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