Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo



Status:Recruiting
Conditions:Infectious Disease
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - Any
Updated:5/5/2014
Start Date:January 2014
Contact:Peter Dicpinigaitis, MD
Email:pdicpini@montefiore.org
Phone:1-917-848-1728

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Antitussive Effect of a Naturally Flavored, Multi-Component Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo

The purpose of this study is to evaluate the antitussive (cough-suppressing) effects of two
liquid medications: a combination of diphenhydramine and phenylephrine in a naturally cocoa
flavoring, and, dextromethorphan syrup, compared with placebo.


Inclusion Criteria:

- healthy adult nonsmokers

- onset of acute, viral upper respiratory tract infection (common cold) within 72
hours of enrollment

Exclusion Criteria:

- smokers

- history of asthma or other respiratory disorders
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