Bone, Endocrine and Lifestyle Longitudinal Study
| Status: | Terminated |
|---|---|
| Conditions: | Osteoporosis |
| Therapuetic Areas: | Rheumatology |
| Healthy: | No |
| Age Range: | 19 - Any |
| Updated: | 4/5/2019 |
| Start Date: | June 2014 |
| End Date: | November 2018 |
The purpose of this proposal is to determine the long-terms effects of hormone and lifestyle
factors on bone health in young women over a 20-year time period. It is our primary
hypothesis that premenopausal women with irregular periods or endocrine issues related to
estrogen will have significantly poorer low back and hip bone health when compared to
regularly menstruating women. It is our secondary hypothesis that long-term assessment of
changes in endocrine function and lifestyle behaviors will assist in establishing risk
factors for osteoporosis in young women. This study will include 1000 premenopausal women.
The women will participate in the collection of a blood sample, bone scan, body fat measures,
and lifestyle questionnaires. In addition, we hope to use this initial study to develop a
group of women to follow throughout menopause, with additional visits occurring every 5 years
over the course of their life.
factors on bone health in young women over a 20-year time period. It is our primary
hypothesis that premenopausal women with irregular periods or endocrine issues related to
estrogen will have significantly poorer low back and hip bone health when compared to
regularly menstruating women. It is our secondary hypothesis that long-term assessment of
changes in endocrine function and lifestyle behaviors will assist in establishing risk
factors for osteoporosis in young women. This study will include 1000 premenopausal women.
The women will participate in the collection of a blood sample, bone scan, body fat measures,
and lifestyle questionnaires. In addition, we hope to use this initial study to develop a
group of women to follow throughout menopause, with additional visits occurring every 5 years
over the course of their life.
Inclusion Criteria:
- Women at least 18 years of age
- free from any uncontrolled chronic disease that may affect bone mass
- Not pregnant
Exclusion Criteria:
- Women recently diagnosed with uncontrolled chronic disease(s) at time of enrollment
known to affect bone mass, including but not limited to metabolic and endocrine
diseases (specifically, diseases of the thyroid and parathyroid glands), osteoporosis,
and those women who have taken prophylactic bone density agents, such as Fosamax.
We found this trial at
1
site
Los Angeles, California 90089
Click here to add this to my saved trials
