Prospective Study to Compare the Efficacy of E.G.Scan to Detect Barrett's Esophagus Compared With Standard Endoscopy

To evaluate the sensitivity and specificity of E.G.Scan (transnasal endoscopy) in diagnosing
Barrett's Esophagus (using standardized endoscopic criteria) compared with the gold standard
white light sedated endoscopy.

To look at the sensitivity and specificity of E.G.Scan (transnsasal endoscopy) in diagnosing
short segment Barrett's Esophagus, esophagitis and hiatus hernia.

Inclusion Criteria:

1. Adult participants aged 18 years or above who are scheduled for routine upper GI
endoscopy for Barrett's Esophagus surveillance, varices surveillance and dyspepsia.

2. Able and willing to give informed consent.

Exclusion Criteria:

1. Patients known to be intolerant to endoscopy.

2. Patients with frequent epistaxis.

3. Patients not clinically fit for endoscopy as judged by their care team.

4. Pregnant women.

5. Patients with allergy/sensitivity to Simethicone (Mylicon), Phenylephrine, Lidocaine
nasal spray, Benzocaine spray (Topex)

6. Use of anticoagulants or antiplatelets.