Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP
| Status: | Completed |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | 18 - 81 |
| Updated: | 4/21/2016 |
| Start Date: | February 2013 |
| End Date: | August 2014 |
Effects of Preoperative Dexamethasone on Postoperative Quality of Recovery Following Vaginal Reconstructive Surgery: A Randomized Controlled Trial
The investigators hypothesize that preoperative administration of 8 mg IV dexamethasone will
benefit patients' perceived quality of recovery after surgery.
benefit patients' perceived quality of recovery after surgery.
This is a randomized controlled trial involving single administration of 8 mg Dexamethasone
per IV preoperatively among women undergoing vaginal reconstructive surgery for pelvic organ
prolapse.
per IV preoperatively among women undergoing vaginal reconstructive surgery for pelvic organ
prolapse.
Inclusion Criteria:
- Women aged 18-81 years old who are scheduled to undergo a major vaginal
reconstructive surgery, including hysterectomy with or without hysterectomy
Exclusion Criteria:
- Daily use of steroids or antiemetic agents such as Zofran, Reglan, Compazine and
Phenargan within one month of surgery
- Regional anesthesia for surgical procedure
- Chronic pain requiring opioid treatment daily
- History of allergy to the study medication
- Severe renal and liver disease
- Pregnancy
- Non English speaking
- Psychiatric disorder that will preclude completion of questionnaires
- Minor surgery that does not involve overnight admission
- Surgery that does not involve hysterectomy or vaginal intraperitoneal apical
suspension
- Hypersensitivity reaction to steroids
- Evidence of systemic fungal infection
- Evidence of any systemic infection
- Uncontrolled diabetes
We found this trial at
1
site
