Evaluating URMC's Massive Transfusion Protocol

The purpose of the study is to evaluate the efficacy of the University of Rochester Medical
Center's current Massive Transfusion Protocol.

Upon arrival of trauma level one designated patients the treating team evaluates the
patient's injuries. If the patient is initiated under the facilities Massive Transfusion
Protocol and meets other inclusion and exclusion criteria the patient will be enrolled in the
study. Study procedures include collection of a blood sample following the transfusion of
each shipment, through shipment 5, of blood products outlined in the current Massive
Transfusion Protocol.

Each blood sample will be run on a Thromboelastograph to evaluate the patient's hematostatic
state through resuscitation. One final blood sample will be collected 24 hours following the
discontinuation of the Massive Transfusion Protocol and also ran on the thromboelastograph.

Due to the critical need for medical intervention, consent procedure will be waived at time
of enrollment. An authorized representative for the patient will be identified and approached
to obtain consent for use of data collected.