ObseRvation of PeripHEral rEtinal Morphology in Normals



Status:Completed
Conditions:Healthy Studies
Therapuetic Areas:Other
Healthy:No
Age Range:20 - 80
Updated:4/21/2016
Start Date:February 2014
End Date:March 2015

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To develop a database of the peripheral retinal circulation using ultra widefield
fluorescein angiography (UWF-FA) imaging for the Optos COE platform. This database will
serve as a quantitative reference tool for the comparison of subjects to a database of known
normal subjects.


Inclusion Criteria:

- Subjects older than 20 years old with good general health.

- Subject is capable of giving consent.

- The subject is able and willing to comply with the study procedures.

- Women with childbearing potential may be included.

- Subjects with ocular media clear enough to allow good quality ocular imaging.

- Normal subjects with no known retinal disease.

Exclusion Criteria:

- Subjects under 20 years old or over 80 years old.

- Subjects with contraindications to dilation

- Subjects with a history of epilepsy.

- Subjects who are or who may be pregnant.

- Subjects with past history of any vitreoretinal disease or surgery such as retinal
detachment, epiretinal membrane, or vitreous hemorrhage.

- Subjects with any ocular condition that interferes with good quality image
acquisition, such as corneal opacities, cataract, and dense vitreous hemorrhage.

- Subjects with any evidence of any retinal or optic nerve disease including glaucoma.

- Subjects with any anterior segment disease with the exception of common ocular
surface disorders (blepharitis, dry eye).

- Subjects with medical conditions that interfere with the subject's compliance to
study procedures such as inability of the subject to maintain steady head or eye
positioning as in patients of ataxia or nystagmus.

- Subjects with a history of Diabetes, High Blood Pressure, Vascular disease
(cardiovascular, peripheral vascular or cerebrovascular)

- Subjects on vasodilators.

- Subject's refusal.
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San Antonio, Texas 78240
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