Leptin Receptors in the Bariatric Surgical Population Within the University of Pittsburgh Medical System: A Cohort Study
| Status: | Completed |
|---|---|
| Conditions: | Obesity Weight Loss |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | October 2013 |
| End Date: | July 2014 |
Prospective cohort study evaluating the role of leptin receptors in the bariatric surgical
population compared with non obese controls. Additionally serum levels of leptin, ghrelin,
motilin and PYY will be compared amongst the different BMI classes and a quality of life
questionnaire completed by all participants.
The hypothesis is that obese individuals have lower leptin receptors in enterocytes which is
partially responsible for the higher serum leptin levels without appropriate control of
satiety.
population compared with non obese controls. Additionally serum levels of leptin, ghrelin,
motilin and PYY will be compared amongst the different BMI classes and a quality of life
questionnaire completed by all participants.
The hypothesis is that obese individuals have lower leptin receptors in enterocytes which is
partially responsible for the higher serum leptin levels without appropriate control of
satiety.
Inclusion Criteria:
- Endoscopic Intervention
Exclusion Criteria:
- 18 years of age or older
- No acute GI bleeding
We found this trial at
1
site
Click here to add this to my saved trials
