Repeated-dose Brief Intervention to Reduce Overdose and Risk Behaviors Among Naloxone Recipients



Status:Active, not recruiting
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 65
Updated:4/21/2016
Start Date:July 2014
End Date:December 2016

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

REBOOT is a pilot randomized trial of a repeated-dose brief intervention to reduce overdose
and risk behaviors among naloxone recipients (REBOOT). It includes an established overdose
education curriculum within an Informational-Motivation-Behavior (IMB) model. This study
will test the feasibility of an efficacy trial of REBOOT vs treatment as usual (information
and referrals) that will evaluate overdose events (non-fatal or death), drug use cessation,
and overdose and HIV risk behaviors, among opioid-dependent persons who have previously
overdosed and already received take-home naloxone (the opioid antagonist used to reverse
overdose).


Inclusion Criteria:

- age 18-65 years;

- current opioid dependence by SCID

- urine positive for opioids during screening, excluding prescribed agonist maintenance
therapy

- history of prior opioid overdose

- previously received take-home naloxone

- no serious illnesses likely to progress clinically during trial

- able and willing to provide informed consent, provide locator information,
communicate in English, adhere to visit schedule

Exclusion Criteria:

- suicidal ideation by concise health risk tracking (CHRT)

- currently participating in another interventional research study that could possible
impact the study's outcomes of interest

- any condition that, in the Principal Investigator's judgment, interferes with safe
study participation or adherence to study procedures
We found this trial at
1
site
Substance Use Research Unit
San Francisco, California 94102
?
mi
from
San Francisco, CA
Click here to add this to my saved trials