Pharmacogenomic Testing Of the Elderly To Reduce Morbidity

Status:	Recruiting
Healthy:	No
Age Range:	18 - Any
Updated:	4/2/2016
Start Date:	April 2014
End Date:	January 2017

The goal of the POETRY Registry is to determine whether data from Pharmacogenomic (PGx)
Testing for elderly and disabled patients can help physicians manage patient medication
regimens and assess if the testing has an effect on reducing adverse drug events,
hospitalizations, and emergency department visits.

The way an individual processes or metabolizes a drug is in part determined by their genes,
and there is known to be genetic variation from one human to another. The study of the way
in which genes affect an individual's response to drugs is known as "Pharmacogenomics."

Inclusion Criteria:

- Subject underwent PGx testing for the alleles appropriate to the target drugs within
the prior 90 days ('index PGx test')

- Males and females aged ≥65 years or male and females aged ≥18 years who have a
disability

- Subject is able and willing to provide written informed consent

- Subject was receiving at least one medication known to be associated with allelic
variation at the time of the index PGx test, including over-the-counter medications

- Subject has a history of at least one target drug-related adverse event (TDAE) over
the 12-month period preceding receipt of PGx test results, or has experienced
inadequate efficacy from a target drug

Exclusion Criteria:

- Subject is currently hospitalized

- Subject's medical and medication history is unavailable over the 90-day period
preceding the receipt of PGx test results

- Subject is unable to provide an accurate history due to mental incapacity

- Subject is known to have undergone prior PGx testing for genes specific to the target
drug(s), exclusive of the PGx test relating to this Registry

We found this trial at

sites

Diagnostic Clinic of Houston

Houston, Texas 77003

from

Houston, TX