Manuka Honey Nasal Rinse Study
| Status: | Completed |
|---|---|
| Conditions: | Sinusitis |
| Therapuetic Areas: | Otolaryngology |
| Healthy: | No |
| Age Range: | 18 - 89 |
| Updated: | 5/5/2014 |
| Start Date: | May 2014 |
| End Date: | December 2015 |
| Contact: | Elizabeth Leon, MD |
| Email: | elizabeth.leon@ent.ufl.edu |
| Phone: | 352.548.6000 |
Effectiveness of Manuka Honey/Saline Nasal Rinses as an Adjunct to Standard Medical Therapy for Chronic Rhinosinusitis: A Prospective Clinical Trial
The purpose of this study is to evaluate whether high-volume nasal rinses with a manuka
honey/saline mixture will improve symptom scores, nasal endoscopic findings and CT scan
findings compared to nasal saline rinse without manuka honey in patients with chronic
rhinosinusitis.
Manuka honey is a honey made from bees that drink the nectar from tea (manuka) trees in New
Zealand. It has been shown to have antibacterial activity against common bacteria that cause
chronic sinusitis.
honey/saline mixture will improve symptom scores, nasal endoscopic findings and CT scan
findings compared to nasal saline rinse without manuka honey in patients with chronic
rhinosinusitis.
Manuka honey is a honey made from bees that drink the nectar from tea (manuka) trees in New
Zealand. It has been shown to have antibacterial activity against common bacteria that cause
chronic sinusitis.
If the subject chooses to participate in the study, the subject will be asked to fill out a
symptom questionnaire at the beginning of the study and at each follow-up visit. The subject
will be randomly assigned (much like the flip of a coin) to one of two treatment arms in
addition to the prescribed medical treatments: 1) nasal rinses twice daily with a saline
solution (standard therapy) or 2) nasal rinses with a saline solution mixed with manuka
honey (the experimental therapy.) Subjects in the manuka honey/saline rinse arm will perform
the experimental rinses twice daily for one month, and then will continue with saline rinses
twice daily, with manuka honey added to the rinses only as needed. Nasal rinsing of some
kind will be continued through the entire study period.
symptom questionnaire at the beginning of the study and at each follow-up visit. The subject
will be randomly assigned (much like the flip of a coin) to one of two treatment arms in
addition to the prescribed medical treatments: 1) nasal rinses twice daily with a saline
solution (standard therapy) or 2) nasal rinses with a saline solution mixed with manuka
honey (the experimental therapy.) Subjects in the manuka honey/saline rinse arm will perform
the experimental rinses twice daily for one month, and then will continue with saline rinses
twice daily, with manuka honey added to the rinses only as needed. Nasal rinsing of some
kind will be continued through the entire study period.
Inclusion Criteria:
- Chronic Rhinosinusitis
- Nasal Polyposis stages 1-3
Exclusion Criteria:
- Nasal Polyposis stage 4-5
- Cystic Fibrosis
- Immunocompromised patients
- Allergy to bees or honey
We found this trial at
2
sites
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