Efficacy of Rectal Infiltration of Exparel for Analgesic Benefit Following Hemorrhoidectomy
| Status: | Terminated |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 21 - 65 |
| Updated: | 12/6/2018 |
| Start Date: | April 2014 |
| End Date: | January 2016 |
Comparison of Rectal Infiltration of Exparel vs. 0.25% Bupivacaine With Epinephrine vs. Placebo for Analgesic Benefit Following Hemorrhoidectomy
The purpose of this study is to compare the quality and duration of pain relief after a
hemorrhoidectomy, provided by locally administered liposomal bupivacaine versus bupivacaine
hcl or control with saline. It is hypothesized that liposomal bupivacaine will provide more
effective postoperative pain relief than both bupivacaine hcl and the control.
hemorrhoidectomy, provided by locally administered liposomal bupivacaine versus bupivacaine
hcl or control with saline. It is hypothesized that liposomal bupivacaine will provide more
effective postoperative pain relief than both bupivacaine hcl and the control.
Inclusion Criteria:
- patients undergoing hemorrhoidectomy for grade 3 or 4 hemorrhoids who are
English-speaking patients, 21-65 yr of age, ASA physical status I-III, BMI<30
Exclusion Criteria:
- contraindications to administration of local anesthesia (e.g., local anesthetic
allergy), difficult airway (Mallampati>2), psychiatric or cognitive disorders,
pregnancy , and history of substance abuse or chronic opioid use
We found this trial at
1
site
New York, New York 10019
Principal Investigator: Ali Shariat, MD
Phone: 914-409-5023
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