Quality of Life (QOL) Following Surgical Treatment for Rectal Cancer

Participant may be eligible to take part in this study if they have not yet had surgery for
rectal cancer or if they had surgery up to 2 years ago.

If participant chooses to take part in this study, they will complete 7 questionnaires about
their quality of life and utilities. Participant will complete the questionnaires before
surgery for rectal cancer (if they have not yet had surgery), and at multiple time points
after the completion of surgery. Participant will receive and return the questionnaires in
the clinic, although if they are unable to come to the clinic for their regular follow-up,
they may be able to receive and return their surveys by mail.

In addition, participant's medical records will be reviewed to learn about what kind of
treatments they may have had, and whether they have had any complications related to their
treatment.

This is an investigational study.

Up to 330 participants will be enrolled on this study. All will be enrolled at MD Anderson.

Inclusion Criteria:

1. Patient has histologically proven adenocarcinoma of the rectum (stage I - IV) that is
planned to be treated by surgical resection performed with curative intent, or who has
already received surgical treatment.

2. Patient is aged 18 and older.

3. Patient must sign an approved informed consent document and have the literary and
physical ability to complete the questionnaire in English.

Exclusion Criteria:

1. Patient has been treated with pelvic radiation therapy for a diagnosis other than
rectal cancer

2. Patient has a concurrent cancer diagnosis at the time of consent

3. Patient has recurrent disease.