Photoacoustic Imaging of the Ovary
| Status: | Terminated |
|---|---|
| Conditions: | Ovarian Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 21 - Any |
| Updated: | 4/17/2018 |
| Start Date: | March 2014 |
| End Date: | May 2016 |
The purpose of this study is to develop technology to image the ovaries in order to better
evaluate ovarian disease and to study how these experimental imaging techniques might work
together or separately to improve our ability to detect ovarian cancer.
evaluate ovarian disease and to study how these experimental imaging techniques might work
together or separately to improve our ability to detect ovarian cancer.
Epithelial ovarian cancer causes the highest mortality of any of the gynecologic cancers
although it is the second most common gynecologic malignancy. Ovarian cancer is not usually
detected earlier than Stage III or IV because it is usually asymptomatic; yet survival is
high with early stage disease. In addition, women with a pelvic mass noted on ultrasound that
undergo oophorectomy have only a 1-3% risk of malignancy and thus 97-99% will be overtreated
because of our inability to reliably differentiate benign from malignant masses with
ultrasound. BRCA1 testing and family history will identify certain high-risk individuals who
have a higher risk of malignancy and need a modality that will be more reliable in detecting
early cancers to provide more accurate surveillance.We are developing a new transvaginal
imaging device optimized for ovarian cancer detection, diagnosis and validated from ex vivo
and in vivo clinical studies. This automated system may provide an early diagnostic tool for
ovarian cancer in the future.
although it is the second most common gynecologic malignancy. Ovarian cancer is not usually
detected earlier than Stage III or IV because it is usually asymptomatic; yet survival is
high with early stage disease. In addition, women with a pelvic mass noted on ultrasound that
undergo oophorectomy have only a 1-3% risk of malignancy and thus 97-99% will be overtreated
because of our inability to reliably differentiate benign from malignant masses with
ultrasound. BRCA1 testing and family history will identify certain high-risk individuals who
have a higher risk of malignancy and need a modality that will be more reliable in detecting
early cancers to provide more accurate surveillance.We are developing a new transvaginal
imaging device optimized for ovarian cancer detection, diagnosis and validated from ex vivo
and in vivo clinical studies. This automated system may provide an early diagnostic tool for
ovarian cancer in the future.
Inclusion Criteria:
- All patients, twenty one years or older, referred to the University of Connecticut for
conditions necessitating oophorectomy.
- Patients cannot be pregnant or wish to become pregnant.
- Willingness to participate in the study.
Exclusion Criteria:
- All Subjects who fail to meet the inclusion criteria are ineligible for the study.
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