Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity

This study will consist of run-in and treatment phases. To qualify for the study,
participants must meet the inclusion/exclusion criteria and return tactile sensitivity
scores within protocol-specified parameters at both the screening and baseline visits.

Run-in will consist of a 2-week period during which participants will use a sodium fluoride
dentifrice. At the start of the first phase, participants will attend a Screening Visit.
They will participate in the informed consent process, complete a medical/dental history,
and be evaluated for tactile sensitivity to Yeaple probe and response to a cold air
stimulus.

Participants who qualify through screening will begin a run-in period that will last
approximately two weeks. The run-in period will be followed by a Baseline visit.
Participants who continue to qualify through Baseline will be randomly assigned to one of
two treatment groups.

During the four-week treatment period, all participants will brush their teeth twice daily
for at least one minute in their usual manner, with their assigned toothpaste. After
brushing, participants will rinse with water, and then rinse with 10 mL of their assigned
experimental mouth rinse for 60 seconds.

The study duration is approximately six weeks with each participant visiting the clinical
site four times.

Adverse events will be observed and collected by querying each participant at each visit for
new or continuing symptoms.

Inclusion Criteria:

- Males and females at least 18 years of age in good general and oral health without
any known allergy to commercial dental products or cosmetics.

- Evidence of a personally signed and dated informed consent document indicating the
subject (or legally acceptable representative) has been informed of all pertinent
aspects of the study

- Females of childbearing potential must be using a medically-acceptable method of
birth control for at least one month prior to Visit 1 and agree to continue using
this method during their participation in the study. Acceptable methods for this
study include:

- Abstinence

- Birth control pills, patches, vaginal rings, implants or injections

- Intrauterine device

- Double barrier method (condom/diaphragm or cervical cap with spermicide)

- Bilateral tubal ligation

- Hysterectomy

- Ovariectomy

- Male partner vasectomy

- Willingness to use the assigned products according to instructions, availability for
appointments, and likelihood of completing the clinical study.

- A minimum of 2 natural premolars, canines, and/or incisors teeth with decay-free
scorable facial/buccal surfaces which must present cervical abrasion, and/or erosion
and/or gingival recession.

- A minimum of two eligible teeth (premolars, canines and/or incisors) with a Screening
(-2 weeks Baseline) and Baseline cold air stimulus Visual Analogue Scale (VAS) score
of 40 - 80 mm on a 100 mm VAS scale, tactile sensitivity score between 10 - 30 grams
after application of the Yeaple probe and a tactile (Yeaple probe) VAS of 40 -80 mm
on a 100 mm VAS scale.

- No more than two eligible teeth per quadrant each separated by 2 other teeth must be
selected.

- Absence of significant oral soft tissue pathology, based on the dentist's visual
examination and at the discretion of the investigator.

- Adequate oral hygiene (i.e. brush teeth daily and exhibit no signs of oral neglect).

- Absence of severe marginal gingivitis, moderate/advanced periodontitis (ADA Type III,
IV) based on a clinical examination and discretion of the Investigator.

- Absence of extensive absence of extensive calculus above the gum line.

Exclusion Criteria:

- Volunteers who report history or presence of kidney disorders, kidney stones, have
celiac disease, inflammatory bowel disease (ulcerative colitis or Crohn's disease),
chronic pancreatitis, have had intestinal or weight-loss surgery, or if have stomach
or intestinal problems that keep them from absorbing certain foods or nutrients.

- Volunteers with eating disorders, uncontrolled Gastroesophageal reflux disease GERD
or Acid Reflux, excessive dietary or environmental exposure to acids, or other
systemic conditions that are predisposing to dentinal hypersensitivity.

- Volunteers with chronic medical debilitating disease associated with constant or
intermittent episodes of daily pain.

- Long-term daily use (≥ 7 consecutive days) of analgesics and any other drugs that at
the discretion of the Investigator would compromise the response of the
hypersensitivity assessments.

- Volunteers who have been using any home-care bleaching, whitening products or have
had a professional bleaching treatment within 4 weeks of the Screening visit.

- Use of desensitizing agents whether prescribed or over-the-counter within eight weeks
prior to screening visit (any sensitivity toothpastes such as Crest Sensitivity,
Sensodyne, Crest Pro-Health, Colgate Sensitivity Relief, any mouthwash and oral care
products used for the treatment of dentinal hypersensitivity).

- Volunteers who during the study will receive dental treatment which may affect their
dentinal hypersensitivity condition (i.e., oral prophylaxis). Emergency treatment
will be allowed.

- Those with a known allergy to study products' ingredients.

- Those requiring antibiotic premedication prior to invasive dental procedures.

- Participation in a dental clinical study involving oral care products within the past
30 days.

- Self reported pregnancy or lactation (this criterion is due to oral tissue changes
related to pregnancy and nursing which can affect interpretation of study results)

- Teeth that are grossly carious, orthodontically banded, abutment teeth for fixed or
removable prostheses, crowned teeth, or third molars will not be included in the
study.

- Periodontal surgery and orthodontic treatment within previous 3 months.

- Extensive restorative treatment (i.e. extensively restored teeth or teeth with
restoration(s) extending into the test area) at the discretion of the Investigator.

- Dental prophylaxis within 2 weeks prior to Screening visit.

- Teeth or periodontium with pathology or defect likely to cause pain.

- Teeth with clinical mobility > grade 1.

- Relative, partner or staff of any clinical research site personnel

- Participation in any clinical study within 30 days of Visit 1.