Study of SPARC1103 in Subjects With Spasticity

Inclusion Criteria:

- Men and women greater than or equal to 18 years of age

- Willing to sign the informed consent form

- Women of child bearing potential willing to practice an acceptable method of birth
control

- Known history of spasticity due to MS

Exclusion Criteria:

- Administration of an investigational drug or device within 30 days prior to Screening
Visit 1

- Unable to comply with trial procedures in the opinion of the Investigator

- Concomitant neurologic conditions causing spasticity

- Any medical condition, including psychiatric disease or epilepsy, which would
interfere with the interpretation of the trial results