Effect of Dietary Fat Cooking Blend on Energy Expenditure in Children (Melt Phase II)
| Status: | Recruiting |
|---|---|
| Conditions: | Obesity Weight Loss |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 15 - 18 |
| Updated: | 4/13/2015 |
| Start Date: | January 2014 |
| Contact: | Andrew Pasternack |
| Phone: | 2125231602 |
Development and Expansion of Melt® Organic Baking Fat for Oxidative Stability and Reducing Child Obesity
The purpose of this study is to test the effects of a cooking oil blend of dietary fats rich
in medium chain triglycerides on energy expenditure and food intake in overweight and obese
adolescents.
in medium chain triglycerides on energy expenditure and food intake in overweight and obese
adolescents.
This study compares the thermic effect of food following consumption of a dietary fat blend
rich in medium chain triglycerides to corn oil in overweight and obese adolescents. Thermic
effect of food will be assessed over up to 6 hours following consumption of a breakfast that
contains 20 g of the test fat. Participants will be asked to rate their levels of appetite
and satiety during the postprandial period and provide information on their prospective food
intake. Blood samples will be taken over a 3-hour period to assess appetite-regulating
hormones and metabolites.
rich in medium chain triglycerides to corn oil in overweight and obese adolescents. Thermic
effect of food will be assessed over up to 6 hours following consumption of a breakfast that
contains 20 g of the test fat. Participants will be asked to rate their levels of appetite
and satiety during the postprandial period and provide information on their prospective food
intake. Blood samples will be taken over a 3-hour period to assess appetite-regulating
hormones and metabolites.
Inclusion Criteria:
- age 15-18
- body mass index 85% percentile or higher for age/sex
- weight stable ±5 lbs in the the 3 months prior
Exclusion Criteria:
- use of medications affecting body weight, cholesterol, or blood pressure
- dietary allergies
- metabolic disorder
- eating disorder
- behavioral or psychological disorders
- endocrine disorder (including type 1 diabetes)
- asthma
- anemia
- use of investigational medications or devices (within past 4 weeks)
- use of over the counter supplements that may effect study endpoints
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