Use of Mobile Technology for Intensive Training in Medication Management

Purpose: Assess whether intensive training with education and daily remote monitoring with
provider involvement has a lasting positive impact on adherence to medication management.
The study will seek to enroll 25 subjects with sickle cell disease or thalassemia, and less
than 100% compliance for taking iron chelators in the previous three month prior to
participation in the study. Subjects will be asked to monitor their daily iron chelator
administration by taking a video recording of preparing it and ingesting at least one sip.
Subjects will also use a medication log to record daily administration of medication, and
meet with study staff monthly for educational activities. The data collected will be
analyzed to describe patient adherence and comfort level with the process of daily recording
of medication management. Mean percent adherence in the pre-study periods and each of the
study periods will be analyzed and compared.