Vegan vs AHA Diet on Inflammation and Glucometabolic Profile in Patients With CAD
| Status: | Completed |
|---|---|
| Conditions: | Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 21 - Any |
| Updated: | 4/26/2018 |
| Start Date: | March 11, 2014 |
| End Date: | March 2018 |
Effects of a Whole-food Plant-based Vegan Diet on Markers of Inflammation and Glucometabolic Profile in Patients With Coronary Artery Disease
In this randomized study the investigators aim to determine the effects of a whole-food
plant-based vegan diet on markers of inflammation and glucometabolic profile in patients with
cardiovascular disease. The investigators hypothesize that a whole-food plant-based vegan
diet will reduce markers of inflammation and improve glucometabolic profile compared with the
American Heart Association (AHA)- recommended diet at 2 months follow-up in patients with
coronary artery disease (CAD). The investigators are also evaluating endothelial function
using the EndoPAT device and stool microbiome.
plant-based vegan diet on markers of inflammation and glucometabolic profile in patients with
cardiovascular disease. The investigators hypothesize that a whole-food plant-based vegan
diet will reduce markers of inflammation and improve glucometabolic profile compared with the
American Heart Association (AHA)- recommended diet at 2 months follow-up in patients with
coronary artery disease (CAD). The investigators are also evaluating endothelial function
using the EndoPAT device and stool microbiome.
Inclusion Criteria:
- Subjects on stable medical therapy for at least 7-10 days post-coronary angiography
and found to have CAD (defined as >50% lesion in an artery with >2mm caliber) .
Exclusion Criteria:
- Failure of the Treatment Self-Regulation Questionnaire
- Use of steroids or non-steroidal anti-inflammatory medications other than aspirin
- Use of probiotics or over the counter supplements other than standard vitamins
- Have a history of myocardial infarction or active infection within the preceding 3
months
- Have a history of an eating disorder or colon cleansing or are already on a whole-food
plant-based vegan diet
- Have a planned PCI during the study period
- Are participating in a competing study
- Have any condition or situation that, in the investigator's opinion, may confound the
study results, or may interfere significantly with the patient's ability to adhere
with study procedures
We found this trial at
1
site
New York, New York 10016
Principal Investigator: Binita Shah, MD, MS
Phone: 212-263-4235
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