Database Registry of the Intermountain Heart Collaborative Study

This is a registry (database) project; there are no investigational treatments, drug or
procedures associated with participation in registry activities. This project is an organized
data gathering and storing (database) endeavor with specific focus on the precursors,
modifiers, biological, and genetic parameters of heart disease and related medical
conditions. Data collection will not immediately influence the course of treatment for any
patient.Sample testing and data utilization for basic science, clinical, and epidemiologic
and publication projects can be initiated using the databank.

The registry will enable researchers to determine best medical practices for predicting,
preventing, and treating heart disease. The registry will: 1) develop standard methods to
collect data and specimens which will be used for research to characterize patients diagnosed
with heart disease as well as healthy controls and to assess differences in demographics and
patient outcomes in both populations; 2) collect, process, and store patients' clinical data
and tissue/blood samples; 3) analyze data collected; 4) use these resources to identify
genes, genetic polymorphisms, genetic mutations, clinical methods and procedures, and/or
biomarkers that predict, prevent, or treat heart disease and/or are associated correlate with
lifestyle or disease outcomes; 5) publish and disseminate results.

Inclusion Criteria:

1. The patient (male or non-pregnant female) must be > 18 years of age.

2. The patient or legally authorized representative must sign a written informed consent,
prior to the procedure, using a form that is approved by the local Institutional
Review Board.

Exclusion Criteria:

1. Neither patient nor patient representative understands spoken English.

2. Neither patient nor the patient's personal representative is willing to give written
consent for participation.

3. Healthy control patients must sign their own consent document.