Pilot Study of Clinician-supported Patient Self-management of Hospital Insulin Therapy



Status:Completed
Conditions:Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - Any
Updated:11/8/2014
Start Date:June 2014
End Date:September 2014
Contact:Charles E Leonard, PharmD, MSCE
Email:celeonar@mail.med.upenn.edu
Phone:215-573-2663

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Proof-of-concept Trial of Clinician-supported Patient Self-management of Hospital Insulin Therapy

This study will examine the feasibility of implementing a clinician-supported patient
self-managed inpatient insulin intervention. It will: assess the number of eligible patients
presenting over time; assess patients' willingness to enroll; assess patients' ability to
successfully complete the intervention; examine occurrences of hyperglycemia and
hypoglycemia; and assess patients' satisfaction with inpatient diabetes care.


Inclusion Criteria:

- Admitted to the Hospital of the University of Pennsylvania (HUP) in the past 72
hours.

- Current HUP location is either Founders 12 or Founders 14.

- Age 18 years or older.

- Type-1 or type-2 diabetes mellitus requiring home basal-bolus insulin therapy
administered via subcutaneous injection (not pump).

- Patient manages own basal-bolus insulin therapy at home without assistance, including
measuring own blood glucose (at least at mealtimes) and administering own
subcutaneous insulin.

- Patient is willing to use the following insulin products: rapid-acting insulin aspart
via insulin pen (NovoLog) and long-acting insulin glargine via vial and syringe
(Lantus).

- Most recent hemoglobin A1c was measured within past 6 months and was <7.5%.

- Active order for in-hospital basal-bolus or sliding-scale insulin.

- Patient is willing and able to record their self-measured blood glucose results,
doses of insulin that they self-administer, a food journal, and exercise log.

- Clinical care team agrees with study inclusion.

Exclusion Criteria:

- Inpatient order for insulin via subcutaneous infusion (i.e., pump) or intravenous
infusion (i.e., drip).

- Inability to perform the activities required by the trial.

- Primary reason for admission was hyperglycemia, hypoglycemia, diabetic ketoacidosis,
hyperglycemic hyperosmolar nonketotic coma, a psychiatric condition, acute alcohol
poisoning, or acute drug ingestion.

- Order for a newly-prescribed or increased dose of a previously-prescribed
corticosteroid.

- Enteral or parenteral nutrition.

- Expected length of stay <48h, as determined by treating physician.

- At risk for self-harm, as determined by 1-to-1 status placement.

- Pregnant, as recorded on medical record.

- Cannot understand, speak, and read English.

- Patient does not wish to utilize Novolog and Lantus while in the hospital.

- Prior enrollment in this trial.

- Do not resuscitate status.

- Inability to give written informed consent.

- Clinical care team disagrees with study inclusion.

- Patient has limited mobility such that they cannot safely access the bedside
medication lockbox.
We found this trial at
1
site
3400 Spruce St
Philadelphia, Pennsylvania 19104
 (215) 662-4000
Hospital of the University of Pennsylvania The Hospital of the University of Pennsylvania (HUP) is...
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from
Philadelphia, PA
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