EffectiveNess and SAfety of Small ANeurysm COiling Trial

This is a prospective cohort study whereby patients who undergo endovascular treatment with
coils for intracranial aneurysms will be studied for initial procedural and 12-18 month
post-treatment outcome. The procedural failure rate (defined above) of treating small
aneurysms with specially designed coils will be compared to pre-specified historical
occurrences. This evaluation will occur within the framework of "non-inferiority" (i.e.
comparable success to coiling of large aneurysms).

Inclusion Criteria:

- Patient presenting with a ruptured or un-ruptured cerebral aneurysm appropriate for
endovascular treatment as determined by the neurovascular team
(neurosurgeon/neurointerventionalist)

- Patients between (and including) 18 and 90 years of age.

- Patient HUNT AND HESS Grade 0-3.

- Where required, patient has given fully informed consent to endovascular coiling
procedure. If patient cannot consent for themselves, appropriate written consent has
been sought from their surrogate, or from appropriate power of attorney.

- Aneurysm < 4mm in maximum diameter.

- Patient is willing and able to return for clinical evaluation and follow-up imaging
evaluation (angiography or MRA) at both 6-months and 12-18 months after endovascular
treatment.

- The aneurysm has not previously been treated (by coiling or clipping).

- A three-dimensional angiogram has been performed.

- Placement of at least one "Nano" coil, at, or at least close to the neck of the
aneurysm.

Exclusion Criteria:

- Patient has more than one aneurysm requiring treatment in the current treatment
session. If a patient has multiple aneurysms, but only one will be treated at the
time of enrollment, they are eligible for the trial. (Additional aneurysms may be
treated at a later date, and may be treated with any coil type that the operator
chooses).

- Patient has an H&H score of 4 or 5 after subarachnoid hemorrhage (SAH).

- Medical or surgical co-morbidity such that the patient's life expectancy is less than
1 year.

- Less than 80% by length of Stryker endovascular coils are implanted.