Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol
| Status: | Completed |
|---|---|
| Conditions: | Food Studies |
| Therapuetic Areas: | Pharmacology / Toxicology |
| Healthy: | No |
| Age Range: | 21 - 45 |
| Updated: | 4/21/2016 |
| Start Date: | March 2014 |
| End Date: | September 2015 |
Relative Effects of Chronic Consumption of Egg Protein at Breakfast With and Without Fiber on Brain Neural Activation, Appetite, Glycemic and Lipemic Control and Self-selected Energy Intake
The objectives of the research are to assess the effects of increased protein and fiber
intake at breakfast on neural activation in brain regions associated with appetitive drive
and reward-driven eating, measures of subjective appetite, and ingestive behavior in
overweight adults. Additional outcomes of interest include the effects of the breakfast
intervention on blood sugar and cholesterol profiles.
intake at breakfast on neural activation in brain regions associated with appetitive drive
and reward-driven eating, measures of subjective appetite, and ingestive behavior in
overweight adults. Additional outcomes of interest include the effects of the breakfast
intervention on blood sugar and cholesterol profiles.
The objectives of the research are to assess the effects of increased protein and fiber
intake at breakfast on neural activation in brain regions associated with appetitive drive
and reward-driven eating, measures of subjective appetite, and ingestive behavior in
overweight adults. Additional outcomes of interest include the effects of the breakfast
intervention on 24-hour glucose profile as well as fasting and postprandial glycemic and
lipemic regulation. The investigators will test the effects of consuming breakfasts with
normal protein/normal fiber (NPNF), normal protein/high fiber (NPHF), high protein/normal
fiber (HPNF), and high protein/high fiber (HPHF) for two weeks in a randomized cross-over
study.
intake at breakfast on neural activation in brain regions associated with appetitive drive
and reward-driven eating, measures of subjective appetite, and ingestive behavior in
overweight adults. Additional outcomes of interest include the effects of the breakfast
intervention on 24-hour glucose profile as well as fasting and postprandial glycemic and
lipemic regulation. The investigators will test the effects of consuming breakfasts with
normal protein/normal fiber (NPNF), normal protein/high fiber (NPHF), high protein/normal
fiber (HPNF), and high protein/high fiber (HPHF) for two weeks in a randomized cross-over
study.
Inclusion Criteria:
- male or female
- age 21 - 45 years
- BMI 25-29.9 kg/m2
Exclusion Criteria:
- Irregular menstrual cycles
- current smoker
- medications or supplements that affect appetite
- pregnant or lactating
- not weight stable
- acutely ill
- diabetic
- claustrophobic
- any implantation unsafe in magnetic resonance imaging (MRI) environment
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