Improving Negative Symptoms of Psychosis In Real-world Environments



Status:Completed
Conditions:Schizophrenia, Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - 65
Updated:5/4/2018
Start Date:July 1, 2014
End Date:February 12, 2018

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This study will compare Cognitive Behavioral Social Skills Training-Compensatory Cognitive
Training (CBSST-CCT) to a goal-focused supportive contact group to see which intervention
better improves symptoms and functioning in people with schizophrenia.


Inclusion Criteria:

MUST BE A RESIDENT OF BROADWAY HOME, SAN DIEGO, OR A SERVICE USER OF THE MEETING PLACE,
ARETA CROWELL, OR PROJECT ENABLE.

1. Voluntary informed consent to participate

2. Age 18 to 65

3. DSM-IV diagnosis of schizophrenia or schizoaffective disorder based on MINI/SCID

4. Moderate-to-severe negative symptoms on the Clinical Assessment Interview for Negative
Symptoms (CAINS total score >19)

5. ≥ 6th grade reading level on the Wide Range Achievement Test-4 Reading subtest (needed
for reading treatment manual)

6. Stable on medications; no changes within 3 months prior to enrollment

Exclusion Criteria:

1. Prior CBT, SST, or CCT in the past 5 years

2. Severe positive symptoms on the Positive and Negative Syndrome Scale (PANSS Delusions,
Disorganization, Hallucinations, or Suspiciousness >5)

3. Severe depression on the Calgary Depression Scale for Schizophrenia (CDSS >8)

4. Ocular damage/disease/surgery/medications that affect pupil dilation

5. DSM-IV alcohol or substance dependence diagnosis in past 6 months based on the MINI or
SCID

6. Level of care required interferes with outpatient therapy (e.g., hospitalized; severe
medical illness) .
We found this trial at
1
site
La Jolla, California 92093
Principal Investigator: Elizabeth Twamley, PhD
Phone: 619-543-6486
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mi
from
La Jolla, CA
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