Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer



Status:Completed
Conditions:Colorectal Cancer, Cancer, Cancer, Cognitive Studies
Therapuetic Areas:Oncology, Psychiatry / Psychology
Healthy:No
Age Range:Any
Updated:7/8/2018
Start Date:April 2003
End Date:August 2006

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Neurological Effects of Chemotherapy and Radiation Treatment: Colon Cancer

RATIONALE: Learning about the long-term effects of chemotherapy and radiation therapy on
brain function may help doctors plan cancer treatments.

PURPOSE: This clinical trial is looking at the neurological effects of chemotherapy and
radiation therapy in patients with colon cancer.

OBJECTIVES:

Primary

- Identify the nature and long-term ramifications of CNS injury as a result of cancer
treatment in patients with colon cancer.

Secondary

- Analyze differences in cognitive measures and MRI data in these patients.

- Correlate MRI measures with cognitive performance in these patients.

OUTLINE: Patients undergo cognitive performance assessment and MRI.

PROJECTED ACCRUAL: A total of 42 patients will be accrued for this study.

DISEASE CHARACTERISTICS:

- Diagnosis of colon cancer

- Received chemotherapy and radiotherapy for colon cancer

PATIENT CHARACTERISTICS:

- Not specified

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics
We found this trial at
1
site
1501 North Campbell Avenue
Tucson, Arizona 85719
(520) 694-CURE (2873)
Arizona Cancer Center at University of Arizona Health Sciences Center Since being established in 1976,...
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mi
from
Tucson, AZ
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