Non-Invasive Oral Biofilm Characterization
| Status: | Recruiting |
|---|---|
| Conditions: | Dental |
| Therapuetic Areas: | Dental / Maxillofacial Surgery |
| Healthy: | No |
| Age Range: | 18 - 25 |
| Updated: | 2/27/2019 |
| Start Date: | June 2014 |
| End Date: | June 2020 |
| Contact: | Petra Wilder-Smith, DDS.PhD |
| Phone: | 949-824-9265 |
There is a need for toothpastes that more effectively remove oral plaque and prevent
re-formation. The objective of this study is to map the development and resolution of
clinical gingivitis using conventional clinical examination and imaging data to determine how
useful imaging techniques can be for evaluating how well a toothpaste cleans the teeth
re-formation. The objective of this study is to map the development and resolution of
clinical gingivitis using conventional clinical examination and imaging data to determine how
useful imaging techniques can be for evaluating how well a toothpaste cleans the teeth
The researcher can use imaging techniques to map changes in gingival blood flow during the
development and resolution of fully reversible, early clinical gingivitis using
standard-of-care clinical indices as gold standard
The researcher can use imaging techniques to map inflammatory microstructural changes in the
oral mucosa including swelling, vasodilation and edema during the development and resolution
of fully reversible, early clinical gingivitis using standard-of-care clinical indices as
gold standard
development and resolution of fully reversible, early clinical gingivitis using
standard-of-care clinical indices as gold standard
The researcher can use imaging techniques to map inflammatory microstructural changes in the
oral mucosa including swelling, vasodilation and edema during the development and resolution
of fully reversible, early clinical gingivitis using standard-of-care clinical indices as
gold standard
Inclusion Criteria:
- Adult male or female 18-25 years of age
- Volunteers with gingivitis but no periodontitis
Exclusion Criteria:
- Subjects who must receive dental treatment during the study dates.
- History of significant adverse effects following use of oral hygiene products such as
toothpastes and mouth rinses. Allergy to personal care/consumer products or their
ingredients.
- Individuals who have taken antibiotics in the previous 3 months
- Individuals who are pregnant or nursing
We found this trial at
1
site
Irvine, California 92612
Principal Investigator: Petra Wilder-Smith, DDS, PhD
Phone: 949-824-9265
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