Evaluation of ETC-1002 in Patients With Hypercholesterolemia and Hypertension



Status:Completed
Conditions:High Blood Pressure (Hypertension), High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 80
Updated:3/31/2019
Start Date:June 2014
End Date:July 2015

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Trial Summary
Trial Overview
Inclusion Criteria

A Placebo-Controlled, Randomized, Double-Blind, Parallel Group Study to Evaluate the Efficacy and Safety of ETC-1002 in Patients With Hypercholesterolemia and Hypertension

This Phase 2 study will assess the efficacy and safety of ETC-1002 monotherapy versus placebo
in patients with hypercholesterolemia and hypertension.


Inclusion Criteria:

- Mean 24-hour ambulatory SBP greater than or equal to 130 mmHg

- or- Mean 24-hour ambulatory DBP greater than or equal to 80 mmHg

- Fasting LDL-C between 100 and 220 mg/dL

- Fasting triglycerides less than 400 mg/dL

- Body mass index (BMI) between 18 and 45 kg/m2

Exclusion Criteria:

- Known or suspected secondary hypertension or history of malignant hypertension

- Taking more than two anti-hypertension medications at the first visit

- History or current clinically significant cardiovascular disease

- History or current type 1 diabetes or type 2 diabetes
We found this trial at
35
sites
Clinical Trial Facility in Hialeah Florida
Hialeah, Florida
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Hialeah, FL
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Clinical Trial Facility in Auburn Maine
Auburn, Maine 04210
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Auburn, ME
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Clinical Trial Facility in Berlin New Jersey
Berlin, New Jersey 08009
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Berlin, NJ
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Clinical Trial Facility in Birmingham Alabama
Birmingham, Alabama
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Birmingham, AL
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Clinical Trial Facility in Butte Montana
Butte, Montana
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Butte, MT
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Clinical Trial Facility in Chandler Arizona
Chandler, Arizona 85224
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Chandler, AZ
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Clinical Trial Facility in Charleston South Carolina
Charleston, South Carolina 29412
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Charleston, SC
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Clinical Trial Facility in Cincinnati Ohio
Cincinnati, Ohio
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Cincinnati, OH
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Clinical Trial Facility in Cincinnati Ohio
Cincinnati, Ohio
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Cincinnati, OH
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Clinical Trial Facility in Corpus Christi Texas
Corpus Christi, Texas
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Corpus Christi, TX
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Clinical Trial Facility in Dallas Texas
Dallas, Texas 75390
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Dallas, TX
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Clinical Trial Facility in Dallas Texas
Dallas, Texas 75390
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Dallas, TX
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Clinical Trial Facility in DeLand Florida
DeLand, Florida 32720
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DeLand, FL
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Clinical Trial Facility in Downingtown Pennsylvania
Downingtown, Pennsylvania 19335
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Downingtown, PA
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Clinical Trial Facility in Endwell New York
Endwell, New York
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Endwell, NY
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Clinical Trial Facility in Eugene Oregon
Eugene, Oregon 97404
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Eugene, OR
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Clinical Trial Facility in Fort Lauderdale Florida
Fort Lauderdale, Florida
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Fort Lauderdale, FL
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Clinical Trial Facility in Gurnee Illinois
Gurnee, Illinois 60031
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Gurnee, IL
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Clinical Trial Facility in Houston Texas
Houston, Texas
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Houston, TX
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Clinical Trial Facility in Indianapolis Indiana
Indianapolis, Indiana 46202
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Indianapolis, IN
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Clinical Trial Facility in Kansas City Kansas
Kansas City, Kansas
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Kansas City, KS
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Clinical Trial Facility in Kenosha Wisconsin
Kenosha, Wisconsin 53142
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Kenosha, WI
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Clinical Trial Facility in Las Vegas Nevada
Las Vegas, Nevada 89135
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Las Vegas, NV
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Clinical Trial Facility in Madison Wisconsin
Madison, Wisconsin 53792
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Madison, WI
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Clinical Trial Facility in Olive Branch Mississippi
Olive Branch, Mississippi 38654
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Olive Branch, MS
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Clinical Trial Facility in Paducah Kentucky
Paducah, Kentucky 42003
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Paducah, KY
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Clinical Trial Facility in Pembroke Pines Florida
Pembroke Pines, Florida 33028
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Pembroke Pines, FL
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Clinical Trial Facility in Pembroke Pines Florida
Pembroke Pines, Florida 33028
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Pembroke Pines, FL
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Clinical Trial Facility in Phoenix Arizona
Phoenix, Arizona
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Phoenix, AZ
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Clinical Trial Facility in Port Orange Florida
Port Orange, Florida
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Port Orange, FL
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Clinical Trial Facility in Salt Lake City Utah
Salt Lake City, Utah
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Salt Lake City, UT
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Clinical Trial Facility in Salt Lake City Utah
Salt Lake City, Utah
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Salt Lake City, UT
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Clinical Trial Facility in Simpsonville South Carolina
Simpsonville, South Carolina
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Simpsonville, SC
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Clinical Trial Facility in Willoughby Hills Ohio
Willoughby Hills, Ohio 44094
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Willoughby Hills, OH
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Clinical Trial Facility in Wilmington North Carolina
Wilmington, North Carolina 28401
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Wilmington, NC
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