Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1



Status:Completed
Conditions:Tobacco Consumers
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - 20
Updated:8/16/2018
Start Date:October 23, 2014
End Date:June 12, 2017

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This study is to examine if inhaled doses of menthol that produce low and high cooling
effects change the appeal of e-cigarettes containing low and high doses of nicotine in
adolescent smokers. The hypothesis is that the combination of nicotine and menthol, when
compared with menthol or nicotine alone, will result in greater increase in liking of an
e-cigarette and greater reduction in nicotine withdrawal.


Inclusion Criteria:

- Ages 18-20 years

- Able to read and write

- Cigarette smoker

- Use of e-cigarettes in the past 30 days

Exclusion Criteria:

- Seeking smoking cessation treatment

- Current/lifetime criteria for dependence on another psychoactive substance -Daily use
of alcohol or marijuana or use of any other drugs including cocaine, opiates,
stimulants

- Regular use of psychoactive drugs including anxiolytics, antidepressants and other
psychostimulants

- Current or past history of psychosis or other psychiatric diagnosis such as major
depression

- Any significant current medical condition
We found this trial at
1
site
New Haven, Connecticut 06519
Principal Investigator: Suchitra Krishnan-Sarin, PhD
Phone: 203-974-7418
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from
New Haven, CT
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