The Lipid Profile of the Skin Surface in Acne
| Status: | Completed |
|---|---|
| Conditions: | Acne, Acne, Dermatology |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 12 - 30 |
| Updated: | 4/21/2016 |
| Start Date: | November 2013 |
| End Date: | July 2015 |
The purpose of this study is to evaluate the differences in the skin lipid profile of
patients with and without acne. Secondly, the goal is to learn more about what the effects
of retinoinds (topical and systemic) are on the the skin lipid profile. We hypothesize that
the skin lipid profile of subjects with acne will be lower in inflammatory lipids in
comparison to subjects without acne.
patients with and without acne. Secondly, the goal is to learn more about what the effects
of retinoinds (topical and systemic) are on the the skin lipid profile. We hypothesize that
the skin lipid profile of subjects with acne will be lower in inflammatory lipids in
comparison to subjects without acne.
Skin lipid profile will be conducted via sebutapes- adhesive tapes that painlessly absorbs
sebum from the face. These tapes will be placed on the face for 1 hour. A photograph of the
face will be taken during each study visit. A sebumeter will also be used to measure skin
sebum secretion rate.
sebum from the face. These tapes will be placed on the face for 1 hour. A photograph of the
face will be taken during each study visit. A sebumeter will also be used to measure skin
sebum secretion rate.
Inclusion Criteria:
- age 12 to 30 years
- have been prescribed tretinoin OR isotretinoin
Exclusion Criteria:
- those who have taken isotretinoin (systemic)
- those who used tretinoin or other topical retinoid within two weeks of starting the
study
- those with seborrheic dermatitis, rosacea, or polycystic ovary syndrome
- those who are pregnant, prisoners, or cognitively impaired
- those who do not fit the inclusion criteria
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