Acetaminophen Use in Labor - Does Use of Acetaminophen Reduce Neuraxial Analgesic Drug Requirement During Labor?
| Status: | Terminated |
|---|---|
| Conditions: | Chronic Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 18 - 55 |
| Updated: | 9/12/2018 |
| Start Date: | September 5, 2013 |
| End Date: | June 2014 |
Does Acetaminophen Reduce Neuraxial Analgesic Requirement During Labor
The hypothesis is if administration of acetaminophen during labor will reduce the amount of
neuraxial pain medication required for comfort. For the study, Acetaminophen or placebo
capsules will be administered at the time of neuraxial analgesia placement and then
administered every 6 hours until delivery. Overall consumption of neuraxial pain medication
will be determined.
neuraxial pain medication required for comfort. For the study, Acetaminophen or placebo
capsules will be administered at the time of neuraxial analgesia placement and then
administered every 6 hours until delivery. Overall consumption of neuraxial pain medication
will be determined.
Acetaminophen 1000 mg or placebo capsules will be administered at the time of neuraxial
analgesia placement and continued every 6 hours until delivery. Vital signs, scores for pain,
nausea, itching, and sleepiness will be also obtained. Evaluation of consumption of neuraxial
analgesic medication will be included in the final analysis for the differences between the 2
groups
analgesia placement and continued every 6 hours until delivery. Vital signs, scores for pain,
nausea, itching, and sleepiness will be also obtained. Evaluation of consumption of neuraxial
analgesic medication will be included in the final analysis for the differences between the 2
groups
Inclusion Criteria:
- >/= 18 years of age not allergic to study medications
Exclusion Criteria:
- pre-eclampsia in labor AND with demonstrated significant abnormal liver enzyme
function changes non-English speaking subjects
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