Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 20 - 50 |
| Updated: | 10/14/2017 |
| Start Date: | June 2014 |
| End Date: | September 2018 |
| Contact: | Jayme C Mancini, PhD, DO |
| Email: | jmancini@nyit.edu |
| Phone: | 5166861237 |
What is the Best Osteopathic Manipulative Medicine (OMM) Approach to Affect Autonomic Nervous System (ANS) Control of Heart Rate Variability (HRV)?
The purpose this study is to determine which manual medicine technique or combination of
techniques has the greatest effect on the natural changes in heart rate.
techniques has the greatest effect on the natural changes in heart rate.
This study intends to examine how three different OMM techniques, sub-occipital release,
rib-raising, and stellate ganglion release, impact autonomic nervous system tone. Subjects
will be randomly assigned to one of four cohort groups, receiving either sub-occipital
release, rib-raising, stellate ganglion release or all three treatment techniques. A shift
towards sympathetic tone will be induced in all subjects using a tilted-to-seated-position
test (Tilt-Seated Position test) and cognitive challenge test, consisting of computerized
questions that become progressively more difficult, and which subjects are asked to answer as
quickly and accurately as possible. These stress tests will be induced twice, once without
any OMM treatment and a second time with the designated OMM treatment(s). The
sympathetic-dependent response to orthostatic change and cognitive challenges will be
determined by Fourier analysis of heart rate variability, recorded using an EKG attached to
each subject.
rib-raising, and stellate ganglion release, impact autonomic nervous system tone. Subjects
will be randomly assigned to one of four cohort groups, receiving either sub-occipital
release, rib-raising, stellate ganglion release or all three treatment techniques. A shift
towards sympathetic tone will be induced in all subjects using a tilted-to-seated-position
test (Tilt-Seated Position test) and cognitive challenge test, consisting of computerized
questions that become progressively more difficult, and which subjects are asked to answer as
quickly and accurately as possible. These stress tests will be induced twice, once without
any OMM treatment and a second time with the designated OMM treatment(s). The
sympathetic-dependent response to orthostatic change and cognitive challenges will be
determined by Fourier analysis of heart rate variability, recorded using an EKG attached to
each subject.
Inclusion Criteria:
- Healthy Individual capable of giving consent between the ages of 20-50
- Normal blood pressure as defined by the Seventh Report of US National Committee on
Prevention, Detection, Education and Treatment of High Blood Pressure
- Normal EKG
- Normal Heart Rate
Exclusion Criteria:
- Chronic Cardiovascular Disease (including but not limited to: congestive heart
failure, previous myocardial infarction, any cardiomyopathy, any arrhythmia, or
previous cardiac surgery)
- Hypertension as defined by the Seventh Report of US National Committee on Prevention,
Detection, Education and Treatment of High Blood Pressure or hypertensive medications
- Smoking
- Asthma
- Pregnancy
- Diabetes
- Current or recent illness (within the past 7 days)
- Any manipulative therapies within the previous 7 days (including but not limited to:
osteopathic manipulative treatment, massage or acupuncture)
- Well conditioned athletes (such as long distance runners)
- Anyone who fails to have an increased heart rate with the passive tilt test (50
degrees head-up)
We found this trial at
1
site
Old Westbury, New York 11568
Phone: 516-686-1237
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