Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis



Status:Completed
Conditions:Arthritis, Rheumatoid Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - Any
Updated:11/1/2018
Start Date:February 5, 2007
End Date:October 26, 2017

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Trial Summary
Trial Overview
Inclusion Criteria

A Long-term, Open-label Follow-up Study Of Tofacitinib (Cp-690,550) For Treatment Of Rheumatoid Arthritis

The purpose of this study is to determine the long-term effectiveness and safety of
CP-690,550 for the treatment of rheumatoid arthritis. Subjects are eligible for this study
only after participating in another "qualifying" study of CP-690,550

A sub-study will be conducted within the A3921024 study, this study will evaluate the immune
response to pneumococcal and influenza vaccines in patients receiving CP-690,550


Inclusion Criteria:

- Subjects who have participated in a randomized "qualifying" study of CP-690,550 for
the treatment of rheumatoid arthritis

Vaccine sub-study visit

- Subjects actively participating in Study A3921024 must have completed at least 3
months of continuous 10 mg BID CP-690,550 treatment in A3921024 as defined by >80%
compliance with prescribed dose consumption of CP-690,550 over the previous 3 months.

Exclusion Criteria:

- Serious medical conditions that would make treatment with CP-690,550 potentially
unsafe

Vaccine sub-study visit

1. Any documented influenza or pneumococcal infection within the last 3 months prior to
randomization in this study

2. Received any vaccine within 1 month prior to randomization in this study

3. Received an influenza vaccine within 6 months or a pneumococcal vaccine within 5 years
of randomization in this study.
We found this trial at
149
sites
Vanderbilt University Medical Center
1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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University of Alabama at Birmingham
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
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Birmingham, AL
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Jacksonville Center for Clinical Research
4085 University Blvd S # 1
Jacksonville, Florida 32216
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Jacksonville, FL
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Borgess Research Institute
1521 Gull Road Kalamazoo
Kalamazoo, Michigan 49048
269-226-4803
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Kalamazoo, MI
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University of California at Los Angeles
Los Angeles, California 90095
310-825-4321
University of California at Los Angeles The University of California, Los Angeles (UCLA) is an...
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Los Angeles, CA
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Miami Research Associates
6141 Sunset Dr # 301
South Miami, Florida 33143
(305) 598-3125
Miami Research Associates Miami Research Associates (MRA) is the largest privately-owned multi-specialty clinical research center...
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South Miami, FL
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The Center for Rheumatology, LLP
Albany, New York 12206
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Albany, NY
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Office of John P. Lavery, MD, PA
Allen, Texas 75013
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Allen, TX
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Asheville Rheumatology & Osteoporosis Research Associates, P.A.
Asheville, North Carolina 28801
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Asheville, NC
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Asheville Rheumatology & Osteoporosis Research Associates, P.A.
Asheville, North Carolina 28801
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Asheville, NC
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Arthritis and Rheumatology of Georgia
Atlanta, Georgia 30342
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Atlanta, GA
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Austin Rheumatology Research PA
Austin, Texas 78705
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Austin, TX
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Arthritis and Rheumatic Disease Specialties
Aventura, Florida 33180
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Aventura, FL
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Ochsner Clinic Foundation-Baton Rouge
Baton Rouge, Louisiana 70809
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Baton Rouge, LA
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Bronson Internal Medicine & Rheumatology
Battle Creek, Michigan 49015
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Battle Creek, MI
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East Penn Rheumatology Associates, P.C.
Bethlehem, Pennsylvania 18015
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Bethlehem, PA
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QUEST Research Institiute
Bingham Farms, Michigan 48025
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Bingham Farms, MI
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Regional Rheumatology Associates
Binghamton, New York 13905
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Binghamton, NY
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St. Luke's Clinic
Boise, Idaho 83702
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Boise, ID
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St. Luke's Clinic - Rheumatology
Boise, Idaho 83702
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Boise, ID
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St. Luke's Intermountain Research Center
Boise, Idaho 83702
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Boise, ID
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Boulder Medical Center
Boulder, Colorado 80304
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Boulder, CO
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OMI- Organizacion Medica de Investigacion
725 Uruguay
Buenos Aires, Caba C1015ABO
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Buenos Aires,
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Physician's Clinic of Iowa, P.C.
Cedar Rapids, Iowa 52401
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Cedar Rapids, IA
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DJL Clinical Research
Charlotte, North Carolina 28210
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Charlotte, NC
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Cincinnati Rheumatic Disease Study Group
Cincinnati, Ohio 45219
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Cincinnati, OH
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Mountain State Clinical Research
Clarksburg, West Virginia 26301
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Clarksburg, WV
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Arthritis Associates And Osteoporosis Center Of Colorado Springs
Colorado Springs, Colorado 80910
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Colorado Springs, CO
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University Physicians - Woodrail Clinic
Columbia, Missouri 65203
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Columbia, MO
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University Of Missouri-Columbia
104 Jesse Hall
Columbia, Missouri 65211
(573) 882-2121
University Of Missouri-Columbia The University of Missouri was founded in 1839 in Columbia, Mo., as...
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Klein & Associates, MD, PA
Cumberland, Maryland 21502
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Cumberland, MD
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Arthritis Care and Diagnostic Center
Dallas, Texas 75321
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Dallas, TX
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Metroplex Clinical Research Center
Dallas, Texas 75231
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Dallas, TX
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Baylor Research Institute
3310 Live Oak St
Dallas, Texas 75204
(214) 820-2687
Baylor Research Institute Baylor Research Institute (BRI) is a dedicated research center for finding prevention...
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Dallas, TX
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STAT Research, Inc.
Dayton, Ohio 45417
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Dayton, OH
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Allergy, Asthma, Arthritis, & Lung
Daytona Beach, Florida 32114
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Daytona Beach, FL
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Physicians Research Alliance
Debary, Florida 32713
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Debary, FL
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Jeffrey D. Lieberman, MD, PC
Decatur, Georgia 30333
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Decatur, GA
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Medical Associates Clinic, PC
Dubuque, Iowa 52001
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Dubuque, IA
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Altoona Center for Clinical Research
Duncansville, Pennsylvania 16635
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Duncansville, PA
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Arthritis and Rheumatology Consultants, P.A.
Edina, Minnesota 55435
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Edina, MN
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Med Investigations
Fair Oaks, California 95628
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Fair Oaks, CA
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University of Connecticut Health Center
263 Farmington Ave
Farmington, Connecticut 06030
(860) 679-2000
University of Connecticut Health Center UConn Health is a vibrant, integrated academic medical center that...
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University of North Texas Health Science Center at Fort Worth
Fort Worth, Texas 76107
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Fort Worth, TX
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Arthritis Treatment Center
Frederick, Maryland 21702
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Frederick, MD
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Southeastern Arthritis Center
Gainesville, Florida 32607
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Gainesville, FL
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Southeastern Imaging & Diagnostics
Gainesville, Florida 32607
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Gainesville, FL
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Southeastern Integrated Medical, PL d/b/a Florida Medical Research Institute
Gainesville, Florida 32607
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Gainesville, FL
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Southeastern Integrated Medical, PL d/b/a Florida Medical Research Institute
Gainesville, Florida 32607
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Gainesville, FL
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ArthroCare, Arthritis Care Research
Gilbert, Arizona 85234
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Gilbert, AZ
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Piedmont Arthritis Clinic, PA
Greenville, South Carolina 29601
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Greenville, SC
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Arthritis & Osteoporosis Center, PC
Hamden, Connecticut 06518
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Hamden, CT
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PMG Research of Hickory, LLC
Hickory, North Carolina 28602
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Hickory, NC
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PMG Research of Hickory, LLC
Hickory, North Carolina 28602
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Hickory, NC
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Arthritis Associates, PLLC
Hixson, Tennessee 37343
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Hixson, TN
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CHI St. Vincent Medical Group Hot Springs
Hot Springs, Arkansas 71913
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Hot Springs, AR
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Accurate Clinical Research
Houston, Texas
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Houston, TX
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Houston Institute for Clinical Research
Houston, Texas 77024
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Houston, TX
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Talbert Medical Group
Huntington Beach, California 92646
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Huntington Beach, CA
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Rheumatology Associates Of North Alabama, P.C.
Huntsville, Alabama 35801
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Huntsville, AL
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Clinical Research Center of Cape Cod, Inc.
Hyannis, Massachusetts 02601
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Hyannis, MA
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Institute of Arthritis Research
Idaho Falls, Idaho 83404
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Idaho Falls, ID
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Diagnostic Rheumatology and Research PC
Indianapolis, Indiana 46227
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Indianapolis, IN
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The Arthritis Clinic
Jackson, Tennessee 38305
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Jackson, TN
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West Tennessee Research Institute
Jackson, Tennessee 38305
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Jackson, TN
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NEA Baptist Clinic
Jonesboro, Arkansas 72401
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Jonesboro, AR
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Rheumatology Consultants Pllc
Knoxville, Tennessee 37909
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Knoxville, TN
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University of California San Diego Center for Innovative Therapy
La Jolla, California 92037
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La Jolla, CA
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Florida Arthritis Center, P.L.
Lake Mary, Florida 32746
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Lake Mary, FL
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BayCare Outpatient Imaging at Bardmoor
Largo, Florida 33777
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Largo, FL
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Dartmouth Hitchcock Medical Center
1 Medical Center Dr
Lebanon, New Hampshire 03756
 (603) 650-5000
Dartmouth Hitchcock Medical Center Dartmouth-Hitchcock is a national leader in patient-centered health care and building...
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Lebanon, NH
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Bluegrass Community Research, Inc
Lexington, Kentucky 40504
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Lexington, KY
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Physician Research Collaboration
Lincoln, Nebraska 68512
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Lincoln, NE
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Osborne Research Center
Little Rock, Arkansas 72201
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Little Rock, AR
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Little Rock Diagnostic Clinic
Little Rock, Arkansas 72205
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Little Rock, AR
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Keck Medicine of USC
Los Angeles, California 90033
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Los Angeles, CA
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University of Southern California (U.S.C.)/ Norris Comprehensive Cancer Center
Los Angeles, California 90033
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Los Angeles, CA
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Ronald Reagan UCLA Medical Center - Drug Information Center
Los Angeles, California 90095
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Los Angeles, CA
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Arthritis & Osteoporosis Associates, LLP
Lubbock, Texas 79424
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Lubbock, TX
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Marietta Rheumatology Associates
Marietta, Georgia 30060
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Marietta, GA
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Clinical Pharmacology Study Group
25 Oak Avenue
Massachusetts, Nebraska 01605
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Massachusetts, NE
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Office of David R. Mandel, MD, Inc.
6551 Wilson Mills Road
Mayfield, Ohio 44143
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Mayfield, OH
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Loyola University Medical Center
2160 South 1st Avenue
Maywood, Illinois 60153
(888) 584-7888
Loyola University Medical Center Loyola University Health System is committed to excellence in patient care...
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Maywood, IL
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St. Luke's Clinic - Rhematology
Meridian, Idaho 83642
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Meridian, ID
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Southwest Rheumatology Research LLC
Mesquite, Texas 75150
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Mesquite, TX
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Center for Arthritis and Rheumatic Diseases
Miami, Florida 33173
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Miami, FL
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Trinity Health Center - Medical Arts
Minot, North Dakota 58701
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Minot, ND
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Illinois Bone and Joint Institute
Morton Grove, Illinois 60053
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Morton Grove, IL
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Jeffrey Alper, MD Research
Naples, Florida 34102
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Naples, FL
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Louisiana State University Health Sciences Center
New Orleans, Louisiana 70112
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New Orleans, LA
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Suncoast Clinical Research, Inc.
New Port Richey, Florida 34652
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New Port Richey, FL
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Delaware Arthritis and Osteoporosis Center
Newark, Delaware 19713
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Newark, DE
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Ocala Rheumatology Research Center
Ocala, Florida 34474
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Ocala, FL
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Oklahoma Medical Research Foundation (OMRF)
Oklahoma City, Oklahoma 73104
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Oklahoma City, OK
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Lynn Health Science Institute
3555 NW 58th St # 800
Oklahoma City, Oklahoma 73112
(405) 447-8839
Lynn Health Science Institute Our mission is to provide clinical trials research and health services...
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Southern Tier Arthritis and Rheumatism
Olean, New York 14760
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Olean, NY
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Westroads Clinical Research
Omaha, Nebraska 68114
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Omaha, NE
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Heartland Clinic Research, Inc.
Omaha, Nebraska 68134
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Omaha, NE
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Gundersen Clinic Ltd
Onalaska, Wisconsin 54650
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Onalaska, WI
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Gundersen Clinic Ltd
Onalaska, Wisconsin 54650
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Onalaska, WI
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Buffalo Rheumatology and Medicine, PLLC
Orchard Park, New York 14127
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