A Study of LY2623091 in Participants With High Blood Pressure

Inclusion Criteria:

- Have a history of hypertension.

- If participants are naïve to treatment of hypertension, or have not been treated with
any antihypertensive medications within the 30 days immediately prior to screening:

- Have seated SBP of ≥140 and <170 millimeters of mercury (mmHg) at screening and
at the end of the lead-in period.

- If participants are currently being treated for hypertension:

- Are taking a stable dose of 1 or 2 antihypertensive medications for at least the
previous 30 days. A combination antihypertensive medication from 2 classes is
considered as 2 antihypertensive medications.

- Are willing to discontinue the antihypertensive medications during the study.

- Have seated SBP of ≥140 and <170 mmHg at the end of the lead-in period.

- Have a body mass index (BMI) ≥18.5 and <40 kilograms/m^2.

Exclusion Criteria:

- Have a history of severe hypertension (defined as SBP ≥180 mmHg and/or DBP ≥120
mmHg), secondary hypertension, symptomatic postural hypotension, or hospitalization
due to hypertension.

- Have SBP ≥180 mmHg and/or DBP ≥110 mmHg at screening, lead-in period, or
randomization.

- Have a history of hospitalization due to hyperkalemia, or history of drug
discontinuation due to elevated serum potassium levels.

- Have a serum potassium ≤3.5 or >5.0 millimoles per liter (mmol/L).

- Have an estimated glomerular filtration rate (eGFR) <50 milliliters/minute/1.73 m^2.