Pulsed Dye Laser in Treating Patients With Post Radiation Dysphonia

PRIMARY OBJECTIVES:

I. To evaluate the use of pulsed dye laser in treatment of the dysphonia that commonly
results after radiation therapy for laryngeal carcinoma.

OUTLINE:

Patients undergo pulsed dye laser monthly for three months.

After completion of study treatment, patients are followed up at 1, 3, and 6 months.

Inclusion Criteria:

- Patients suffering from dysphonia after radiation therapy for glottic carcinoma will
be included in the study

- Patients will be included if their initial stage was T1 N0 M0 or T2 N0 M0

Exclusion Criteria:

- Patients having previously undergone large surgical resections of the larynx or
hypopharynx will be excluded

- Patients fewer than 1 year out from completion of radiation therapy will be excluded

- Patients with local disease recurrence would be excluded from the trial

- Patients in whom the transnasal endoscope is poorly tolerated or patients in whom
transnasal endoscopic laryngoscopy is contraindicated will be excluded