Using Electrical Bioimpedance Assessments to Estimate Perioperative Total Body Water and Postoperative Fluid Need



Status:Completed
Conditions:Cancer, Cancer, Gastroesophageal Reflux Disease , Gastrointestinal, Diverticulitis, Pancreatic Cancer
Therapuetic Areas:Gastroenterology, Oncology
Healthy:No
Age Range:18 - 80
Updated:8/30/2018
Start Date:May 2012
End Date:July 2015

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The Use of Multifrequency Bioimpedance Assessments as an Estimate of Perioperative Total Body Volume and Postoperative Fluid Resuscitation

Being able to accurately monitor patient bodily fluid levels during and after surgery is very
important, as there are a number of complications that can arise if a patient's fluid levels
become unbalanced, such as swelling within or pressure on various bodily organ systems. There
are several different ways that physicians can monitor a patient's fluid balance during and
after surgery, such as measuring the amount of urine output or the use of central venous
catheters which measure the pressure in the veins entering the heart. Most of these
techniques are invasive since they require tubes to be inserted into the body. A potential
alternative would be to use a noninvasive technique such as electrical bioimpedance (BIA).

Bioimpedance assessments work by using small electrical currents that can accurately predict
both the water surrounding the outside of cells in the body, as well as the total amount of
water in the entire body. Electrical bioimpedance assessments have been used to estimate
patient swelling following surgery (edema), to measure the volume of blood the heart is
pumping out, as well as to calculate body fat percentages.

The goal of this study is to relate this technology to fluid shifts within the body that
occur as a result of surgery, in particular, major intra-abdominal surgeries. By using
bioimpedance during and after surgery, the investigators will compare the data collected with
that calculated by using traditional measures of body fluid status, such as urine output and
intraoperative blood loss. During the study, the bioimpedance monitors will not replace the
standard bodily fluid monitors and will not interfere with their readings. Additionally, the
electrical current produced by the bioimpedance monitors is too small for patients to feel
and will not interfere with medical devices such as pacemakers.

Being able to accurately monitor patient bodily fluid levels during and after surgery is very
important, as there are a number of complications that can arise if a patient's fluid levels
become unbalanced, such as swelling within or pressure on various bodily organ systems. There
are several different ways that physicians can monitor a patient's fluid balance during and
after surgery, such as measuring the amount of urine output or the use of central venous
catheters which measure the pressure in the veins entering the heart. Most of these
techniques are invasive since they require tubes to be inserted into the body. A potential
alternative would be to use a noninvasive technique such as electrical bioimpedance (BIA).

Bioimpedance assessments work by using small electrical currents that can accurately predict
both the water surrounding the outside of cells in the body, as well as the total amount of
water in the entire body. Electrical bioimpedance assessments have been used to estimate
patient swelling following surgery (edema), to measure the volume of blood the heart is
pumping out, as well as to calculate body fat percentages.

The goal of this study is to relate this technology to fluid shifts within the body that
occur as a result of surgery, in particular, major intra-abdominal surgeries. By using
bioimpedance during and after surgery, the investigators will compare the data collected with
that calculated by using traditional measures of body fluid status, such as urine output and
intraoperative blood loss. During the study, the bioimpedance monitors will not replace the
standard bodily fluid monitors and will not interfere with their readings. Additionally, the
electrical current produced by the bioimpedance monitors is too small for patients to feel
and will not interfere with medical devices such as pacemakers.

Inclusion Criteria:

- Patients having major intra-abdominal procedures under general anesthesia requiring
hospitalization postoperatively during the initial recovery from surgery.

Exclusion Criteria:

- Patients not having intra-abdominal procedures (ie. Thyroidectomy, open or
laparoscopic inguinal hernia repair, excision of skin lesions, breast procedures)

- Patients having outpatient surgery

- Patients having laparoscopic cholecystectomies, laparoscopic or open appendectomies

- Patients having bariatric surgery (because the bioimpedance assessment technology has
proven to be unreliable in obese populations)

- Morbidly obese patients (BMI >40)

- Unable to provide informed consent

- Pregnant women
We found this trial at
1
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620 John Paul Jones Cir
Portsmouth, Virginia 23708
(757) 953-5008
Naval Medical Center - Portsmouth Naval Medical Center Portsmouth, Virginia has proudly served the military...
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Portsmouth, VA
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