Study to Image the Esophagus Using the OFDI Capsule

A total of 54 subjects comprising of healthy volunteers, patients with Eosinophilic
Esophagitis (EoE) or Barrett's Esophagus will be asked to swallow the OFDI capsule while
being unsedated. The capsule is attached to a tether that allows the capsule operator to
navigate the capsule as it progresses down the esophagus using natural propulsion called
peristalsis as well as to bring it back up to pulled out of the mouth when the procedure is
done.

As the capsule progresses down the esophagus, multiple, two dimensional, microscopic cross-
sectional images of the esophagus are acquired.

Inclusion Criteria:

- A previous diagnosis of Barrett's Esophagus

- OR a previous diagnosis of EoE

- OR a previous diagnosis of Gastroesophageal reflux disease (GERD)

- Subject must be 18 years or older in case of Barrett's and GERD, and over the age of
16 years for EoE

- Subject must be able to give informed consent

Exclusion Criteria:

- Subjects with known esophageal strictures, intestinal strictures or dysphagia

- OR subjects with a history of prior GI surgery or GI Intestinal Crohn's disease