Urinary Leukotriene E4 Levels in Children With Obstructive Sleep Apnea



Status:Completed
Conditions:Insomnia Sleep Studies, Pulmonary, Pulmonary
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:2 - 16
Updated:2/8/2018
Start Date:February 2014
End Date:December 2016

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Investigate urinary leukotriene E4 levels and determine if there is a correlation with
severity of obstructive sleep apnea. The investigators then would like to determine a
threshold level which could then be used for confirmation of diagnosis of obstructive sleep
apnea (OSA).


Inclusion Criteria:

- children 2-16 years of age

- scheduled for polysomnogram

Exclusion Criteria:

- cardiovascular, neuromuscular, immunologic or craniofacial disorders

- pharmacologic treatment including corticosteroids and leukotriene receptor antagonists
in the last month

- subjects who have already received treatment for OSA with an oral appliance,
continuous positive airway pressure (CPAP) device

- previously undergone tonsillectomy and/or adenoidectomy
We found this trial at
1
site
601 Children's Lane
Norfolk, Virginia 23507
(757) 668-7000
Children's Hospital of The King's Daughters Children
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mi
from
Norfolk, VA
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