Incidence of Non Receptive Endometrium in Obese Women
| Status: | Completed |
|---|---|
| Conditions: | Women's Studies, Infertility |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 12/15/2017 |
| Start Date: | August 2014 |
| End Date: | July 31, 2017 |
Incidence of Not Receptive Endometrium During the Window of Implantation as Body Mass Index by Testing ERA.
This study evaluates the incidence of Non Receptive endometrium in obese infertile women
compared to infertile normal weight women using Endometrial Receptivity Array (ERA) test,
containing 238 genes, identifying the receptivity status of an endometrial sample and
diagnosing the patient's Window of Implantation, regardless of the histological appearance of
the sample. An endometrial biopsy is collected from the uterine fundus, either in a natural
cycle or in a hormonal replacement therapy (HRT) cycle and the test is performed.
compared to infertile normal weight women using Endometrial Receptivity Array (ERA) test,
containing 238 genes, identifying the receptivity status of an endometrial sample and
diagnosing the patient's Window of Implantation, regardless of the histological appearance of
the sample. An endometrial biopsy is collected from the uterine fundus, either in a natural
cycle or in a hormonal replacement therapy (HRT) cycle and the test is performed.
Inclusion Criteria:
- Infertile women: > 1 year of regular unprotected intercourse without evidence of
pregnancy.
- Normal uterus by 2D/3D ultrasound scan and/or hysteroscopy
- No endometriosis
- Presence of both ovaries
- < 45 years old (in ovum donation, outcome parameters are not affected until this age
in all the current published studies).
Exclusion Criteria:
- Hydrosalpinx
- Stage 3-4 endometriosis diagnosed with ultrasound, laparoscopy/ laparotomy.
- Implantation failure (≥ 4 pre-embryos of good quality transferred without pregnancy)
- Recurrent pregnancy loss (≥ 2 pregnancies biochemical / clinical)
We found this trial at
3
sites
Baylor College of Medicine Baylor College of Medicine in Houston, the only private medical school...
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials