Incidence of Non Receptive Endometrium in Obese Women

Status:	Completed
Conditions:	Women's Studies, Infertility
Therapuetic Areas:	Reproductive
Healthy:	No
Age Range:	18 - 45
Updated:	12/15/2017
Start Date:	August 2014
End Date:	July 31, 2017

Incidence of Not Receptive Endometrium During the Window of Implantation as Body Mass Index by Testing ERA.

This study evaluates the incidence of Non Receptive endometrium in obese infertile women
compared to infertile normal weight women using Endometrial Receptivity Array (ERA) test,
containing 238 genes, identifying the receptivity status of an endometrial sample and
diagnosing the patient's Window of Implantation, regardless of the histological appearance of
the sample. An endometrial biopsy is collected from the uterine fundus, either in a natural
cycle or in a hormonal replacement therapy (HRT) cycle and the test is performed.

Inclusion Criteria:

- Infertile women: > 1 year of regular unprotected intercourse without evidence of
pregnancy.

- Normal uterus by 2D/3D ultrasound scan and/or hysteroscopy

- No endometriosis

- Presence of both ovaries

- < 45 years old (in ovum donation, outcome parameters are not affected until this age
in all the current published studies).

Exclusion Criteria:

- Hydrosalpinx

- Stage 3-4 endometriosis diagnosed with ultrasound, laparoscopy/ laparotomy.

- Implantation failure (≥ 4 pre-embryos of good quality transferred without pregnancy)

- Recurrent pregnancy loss (≥ 2 pregnancies biochemical / clinical)

We found this trial at

sites

IVI Valencia

Valencia, 46015

Principal Investigator: Jose Bellver, MD PhD

Phone: 963050900

from

Valencia,