Nighttime Protein Intake on Overnight Lipolysis and Morning Fat Oxidation in Obese Men



Status:Completed
Conditions:Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 45
Updated:4/21/2016
Start Date:July 2014
End Date:August 2015

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Trial Summary
Trial Overview
Inclusion Criteria

The Effect of Nighttime Protein Intake on Overnight Lipolysis and Morning Fat Oxidation in Obese Men.

Single macronutrients will be consumed before sleep by obese men. Overnight lipolysis will
be measured with the microdialysis technique by measuring glycerol concentration and blood
flow in abdominal adipose tissue. Morning fat oxidation will be measured with indirect
calorimetry.

The investigators hypothesize that carbohydrate intake will blunt the overnight lipolysis
rate compared to casein protein and a non-caloric placebo. The investigators also
hypothesize that casein and placebo will not be significantly different from each other in
terms of overnight lipolysis.


Inclusion Criteria:

- Healthy, sedentary overweight or obese (BMI ≥25 kg/m^2; body fat ≥ 25% ) men

Exclusion Criteria:

- Men that have been exercising for more than 2 days per week for more than 45 minutes
per session (within the past 6 months), have uncontrolled hypertension (Blood
Pressure (BP)>160/100 mmHg, diagnosed cardiovascular disease, stroke, diabetes,
thyroid or kidney dysfunction, take cholesterol medication, or have any allergies to
milk products will be excluded. Smokers will also be excluded.
We found this trial at
1
site
Institute of Sports Science and Medicine, Florida State University
Tallahassee, Florida 32306
?
mi
from
Tallahassee, FL
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