A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol



Status:Terminated
Conditions:High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:4/17/2018
Start Date:October 2014
End Date:December 2015

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

The Addition of Evacetrapib to Atorvastatin Compared to Placebo, High Intensity Atorvastatin, and Atorvastatin With Ezetimibe to Evaluate LDL-C Lowering in Patients With Primary Hyperlipidemia - The ACCENTUATE Study

The purpose of the ACCENTUATE study is to evaluate whether the study drug known as
evacetrapib is effective in treating participants with high cholesterol and atherosclerotic
cardiovascular disease (ASCVD) and/or diabetes.


Inclusion Criteria:

- Must be treated with atorvastatin 40 mg/day for at least 30 days prior to screening

- Have an LDL-C >70 mg/deciliter(dL) or non-HDL-C >100 mg/dL

- Have screening triglycerides ≤400 mg/dL (≤4.5 millimoles/Liter)

- Individuals with ASCVD and/or individuals with type 1 or type 2 diabetes

Exclusion Criteria:

- Have a hemoglobin A1c (HbA1c) >9.5%

- New York Heart Association (NYHA) class III or IV congestive heart failure

- History of either a transient ischemic stroke or ischemic stroke <30 days

- History of acute coronary syndrome (ACS) <30 days
We found this trial at
62
sites
Medex Healthcare Research, Inc.
Saint Louis, Missouri 63117
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Avail Clinical Research
860 Peachwood Drive
DeLand, Florida 32720
(386) 740-0770
Site Overview Avail Clinical Research is a renowned and experienced clinical research site conducting Phase...
?
mi
from
DeLand, FL
Click here to add this to my saved trials
Suncoast Research Group, LLC
2128 W Flagler St # 201
Miami, Florida 33144
?
mi
from
Miami, FL
Click here to add this to my saved trials
Northwest Heart Clinical Research
Arlington Heights, Illinois 60005
?
mi
from
Arlington Heights, IL
Click here to add this to my saved trials
Asheville Cardiology Associates
Asheville, North Carolina 28802
?
mi
from
Asheville, NC
Click here to add this to my saved trials
University of Colorado Health Sciences Ctr.
Aurora, Colorado 80045
?
mi
from
Aurora, CO
Click here to add this to my saved trials
Maryland Cardiovascular Specialists
Baltimore, Maryland 21229
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Overlea Personal Physicians
Baltimore, Maryland 21236
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Northwest Clinical Research Center
Bellevue, Washington 98007
?
mi
from
Bellevue, WA
Click here to add this to my saved trials
Grace Research, LLC
Bossier City, Louisiana 71111
?
mi
from
Bossier City, LA
Click here to add this to my saved trials
Zasa Clinical Research
Boynton Beach, Florida 33437
?
mi
from
Boynton Beach, FL
Click here to add this to my saved trials
Advanced Clinical Research
Carmichael, California 95608
?
mi
from
Carmichael, CA
Click here to add this to my saved trials
Metrolina Internal Medicine
Charlotte, North Carolina 28204
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
Cedar-Crosse Research Center
Chicago, Illinois 60607
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Cardiac Research
Colorado Springs, Colorado 80909
?
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
Aventiv Research
Columbus, Ohio 43213
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Georgia Heart Specialists
Covington, Georgia 30014
?
mi
from
Covington, GA
Click here to add this to my saved trials
Midwest CRC
Crystal Lake, Illinois 60012
?
mi
from
Crystal Lake, IL
Click here to add this to my saved trials
Partners in Clinical Research, LLC
Cumberland, Rhode Island 02864
?
mi
from
Cumberland, RI
Click here to add this to my saved trials
Cardiology Research Assoc.
Daytona Beach, Florida 32117
?
mi
from
Daytona Beach, FL
Click here to add this to my saved trials
Tooraj Joseph Raoof M.D., Inc.
Encino, California 91436
?
mi
from
Encino, CA
Click here to add this to my saved trials
Lillestol Research LLC
Fargo, North Dakota 58103
?
mi
from
Fargo, ND
Click here to add this to my saved trials
Alan Graff, MD, PA
Fort Lauderdale, Florida 33308
?
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
United Osteoporosis Center
Gainesville, Georgia 30501
?
mi
from
Gainesville, GA
Click here to add this to my saved trials
High Point Clinical Trials Center
High Point, North Carolina 27265
?
mi
from
High Point, NC
Click here to add this to my saved trials
East West Medical Institute
Honolulu, Hawaii 96814
?
mi
from
Honolulu, HI
Click here to add this to my saved trials
Heart Center Research, Llc
Huntsville, Alabama 35801
?
mi
from
Huntsville, AL
Click here to add this to my saved trials
Hutchinson Clinic
Hutchinson, Kansas 67502
?
mi
from
Hutchinson, KS
Click here to add this to my saved trials
Cape Cod Research Institute
Hyannis, Massachusetts 02601
?
mi
from
Hyannis, MA
Click here to add this to my saved trials
Indiana Heart Physicians
Indianapolis, Indiana 46237
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Midwest Institute for Clinical Research
Indianapolis, Indiana 46260
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Nature Coast Clinical Research
Inverness, Florida 34452
?
mi
from
Inverness, FL
Click here to add this to my saved trials
Irvine Clinical Research Center
Irvine, California 92618
?
mi
from
Irvine, CA
Click here to add this to my saved trials
Clinical Investigation Specialists
Kenosha, Wisconsin 53142
?
mi
from
Kenosha, WI
Click here to add this to my saved trials
Holston Medical Group Clinical Research
Kingsport, Tennessee 37660
?
mi
from
Kingsport, TN
Click here to add this to my saved trials
Palm Research Center
Las Vegas, Nevada 89102
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
VA Long Beach Healthcare System
Long Beach, California 90822
?
mi
from
Long Beach, CA
Click here to add this to my saved trials
Community Medical Associates Inc
Louisville, Kentucky 40207
?
mi
from
Louisville, KY
Click here to add this to my saved trials
Solaris Clinical Research
Meridian, Idaho 83646
?
mi
from
Meridian, ID
Click here to add this to my saved trials
Desert Clinical Research
Mesa, Arizona 85201
?
mi
from
Mesa, AZ
Click here to add this to my saved trials
ActivMed Practices & Research
Methuen, Massachusetts 01844
?
mi
from
Methuen, MA
Click here to add this to my saved trials
PMG Research of Charleston, LLC
Mount Pleasant, South Carolina 29464
?
mi
from
Mount Pleasant, SC
Click here to add this to my saved trials
Medex Healthcare Research, Inc.
New York, New York 10004
?
mi
from
New York, NY
Click here to add this to my saved trials
South Oklahoma Heart Research
Oklahoma City, Oklahoma 73135
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Central Phoenix Medical Clinic
Phoenix, Arizona 85020
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Research and Cardiovascular Corp.
Ponce, 00717
?
mi
from
Ponce,
Click here to add this to my saved trials
Progressive Medical Research
Port Orange, Florida 32127
?
mi
from
Port Orange, FL
Click here to add this to my saved trials
Portland Preventive Cardiology, LLC
Portland, Oregon 97225
?
mi
from
Portland, OR
Click here to add this to my saved trials
Rancho Cucamonga Clinical
Rancho Cucamonga, California 91730
?
mi
from
Rancho Cucamonga, CA
Click here to add this to my saved trials
Black Hills Cardiovascular Research Group
Rapid City, South Dakota 57701
?
mi
from
Rapid City, SD
Click here to add this to my saved trials
National Clinical Research - Richmond, Inc.
Richmond, Virginia 23294
?
mi
from
Richmond, VA
Click here to add this to my saved trials
Boice-Willis Clinic
Rocky Mount, North Carolina 27804
?
mi
from
Rocky Mount, NC
Click here to add this to my saved trials
Saratoga Clinical Research LLC
Saratoga Springs, New York 12866
?
mi
from
Saratoga Springs, NY
Click here to add this to my saved trials
Heart and Vascular Center of New Brunswick LLC
Somerset, New Jersey 08873
?
mi
from
Somerset, NJ
Click here to add this to my saved trials
Kootenai Heart Clinics
Spokane, Washington 99204
?
mi
from
Spokane, WA
Click here to add this to my saved trials
Encompass Clinical Research
Spring Valley, California 91978
?
mi
from
Spring Valley, CA
Click here to add this to my saved trials
Northwest Houston Heart Center
Tomball, Texas 77375
?
mi
from
Tomball, TX
Click here to add this to my saved trials
University Clinical Investigators
Tustin, California 92780
?
mi
from
Tustin, CA
Click here to add this to my saved trials
Diablo Clinical Research Inc
Walnut creek, California 94598
?
mi
from
Walnut creek, CA
Click here to add this to my saved trials
Cardiology Partners Clinical Research Institute
Wellington, Florida 33449
?
mi
from
Wellington, FL
Click here to add this to my saved trials
Buffalo Cardiology & Pulmonary Associates
Williamsville, New York 14221
?
mi
from
Williamsville, NY
Click here to add this to my saved trials
PMG Research of Wilmington
1907 Tradd Ct
Wilmington, North Carolina 28401
(910) 799-5500
PMG Research of Wilmington PMG Research of Wilmington has two offices situated in a 1...
?
mi
from
Wilmington, NC
Click here to add this to my saved trials