Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Primary Hyperlipidemia or Mixed Dyslipidemia At Risk Of Cardiovascular Events



Status:Completed
Conditions:High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:8/2/2018
Start Date:October 28, 2014
End Date:July 10, 2017

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Trial Summary
Trial Overview
Inclusion Criteria

A 52 Week Phase 3 Double-blind, Randomized, Placebo-controlled, Parallel-group Study To Assess The Efficacy, Safety And Tolerability Of Pf-04950615 In Subjects With Primary Hyperlipidemia Or Mixed Dyslipidemia At Risk Of Cardiovascular Events

This study is a multicenter, double-blind, randomized study to access the efficacy, safety
and tolerability of Bococizumab (PF-04950615; RN316) in subjects with hyperlipidemia
receiving background statin therapy.


Inclusion Criteria:

- Treated with a statin

- Fasting LDL-C >=100 mg/dL and triglyceride <= 400 mg/dL

- High or very high risk of incurring a cardiovascular event

Exclusion Criteria:

- Pregnant or breastfeeding females

- Cardiovascular or cerebrovascular event or procedure within 90 days

- Congestive heart failure NYHA class IV

- Poorly controlled hypertension
We found this trial at
107
sites
Wake Internal Medicine Consultants, Inc.
Raleigh, North Carolina 27612
1068
mi
from
Raleigh, NC
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Accord Clinical Research
3635 S. Clyde Morris Blvd
Port Orange, Florida 32129
386-760-3862
About Us Accord Clinical Research is a privately owned research facility, founded in Port Orange,...
1132
mi
from
Port Orange, FL
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Millennium Clinical Trials, L.L.C.
3801 N. Fairfax Drive
Arlington, Virginia 22203
703-527-8100
1123
mi
from
Arlington, VA
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Millennium Clinical Trials, L.L.C.
3801 N. Fairfax Drive
Arlington, Virginia 22203
703-527-8100
1123
mi
from
Arlington, VA
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Renstar Medical Research
104 SE 1st Avenue
Ocala, Florida 34471
352-629-5800
1078
mi
from
Ocala, FL
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Clinical Trials of Texas, Inc.
7940 Floyd Curl Dr.
San Antonio, Texas 78229
210-949-0122
570
mi
from
San Antonio, TX
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Clinical Trials of Texas, Inc.
7940 Floyd Curl Dr.
San Antonio, Texas 78229
210-949-0122
570
mi
from
San Antonio, TX
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Spartanburg Medical Research
485 Simuel Road.
Spartanburg, South Carolina 29303
(864) 583-1556
900
mi
from
Spartanburg, SC
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Castlerock Clinical Research Consultants, LLC
6804 South Canton
Tulsa, Oklahoma 74136
918-524-5205
156
mi
from
Tulsa, OK
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Heartland Research Associates, LLC
1709 S Rock Rd
Wichita, Kansas 67207
316-689-6629
32
mi
from
Wichita, KS
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Heartland Research Associates, LLC
1709 S Rock Rd
Wichita, Kansas 67207
316-689-6629
32
mi
from
Wichita, KS
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Albuquerque Clinical Trials
Albuquerque, New Mexico
523
mi
from
Albuquerque, NM
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Advanced Cardiovascular, LLC Research
Alexander City, Alabama 35010
745
mi
from
Alexander City, AL
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Advanced Cardiovascular, LLC, Research
Auburn, Alabama 36830
781
mi
from
Auburn, AL
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Heartland Research Associates, LLC
Augusta, Kansas 67010
46
mi
from
Augusta, KS
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University of Colorado Hospital
12605 East 16th Avenue
Aurora, Colorado 80045
720-848-0000
University of Colorado Hospital, Site Top medical professionals, superior medicine and progressive change make University...
400
mi
from
Aurora, CO
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American Health Network Of Indiana Llc
Avon, Indiana 46123
630
mi
from
Avon, IN
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Bethesda Health Research
Bethesda, Maryland 20817
1121
mi
from
Bethesda, MD
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BRCR Medical Center, Inc.
Boca Raton, Florida 33432
1300
mi
from
Boca Raton, FL
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Boca Raton Clinical Research Associates
Boca Raton, Florida 33432
1299
mi
from
Boca Raton, FL
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Northwest Clinical Trials
Boise, Idaho 83704
1046
mi
from
Boise, ID
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Meridien Research
Brooksville, Florida
1093
mi
from
Brooksville, FL
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LMC Clinical Research Inc. (Calgary)
Calgary, Alberta
1214
mi
from
Calgary,
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Punzi Medical Center
Carrollton, Texas 75006
335
mi
from
Carrollton, TX
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Medical Research South
Charleston, South Carolina 29407
1059
mi
from
Charleston, SC
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Clinical Research Advantage, Inc. / Colorado Springs Family Practice
Colorado Springs, Colorado 80909
386
mi
from
Colorado Springs, CO
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Ellipsis Research Group, LLC
Columbia, South Carolina 29201
973
mi
from
Columbia, SC
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Linfritz Research Institute Inc.
Coral Gables, Florida 33134
1318
mi
from
Coral Gables, FL
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Primed Clinical Research
Dayton, Ohio 45419
746
mi
from
Dayton, OH
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Creekside Endocrine Associates PC
Denver, Colorado 80209
407
mi
from
Denver, CO
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Centennial Medical Group
Elkridge, Maryland
1142
mi
from
Elkridge, MD
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McLaren Flint
Flint, Michigan 48532
826
mi
from
Flint, MI
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Florida Health Center
Fort Lauderdale, Florida 33312
1307
mi
from
Fort Lauderdale, FL
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Clinical Research Advantage, Inc./Prairie Fields Family Medicine, PC
Fremont, Nebraska 68025
263
mi
from
Fremont, NE
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Stern Cardiovascular Foundation
Germantown, Tennessee 38138
481
mi
from
Germantown, TN
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Physician's East
Greenville, North Carolina 27834
1139
mi
from
Greenville, NC
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Physician's East
Greenville, North Carolina 27834
1139
mi
from
Greenville, NC
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Physician's East Endocrinology
Greenville, North Carolina 27834
1140
mi
from
Greenville, NC
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Harleysville Medical Associates
Harleysville, Pennsylvania 19438
1213
mi
from
Harleysville, PA
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Health Care Family Rehab & Research Center
Hialeah, Florida 33012
1314
mi
from
Hialeah, FL
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Indago Research & Health Center, Inc.
Hialeah, Florida 33012
1312
mi
from
Hialeah, FL
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Clinical Trials of America Inc
Hickory, North Carolina 28601
921
mi
from
Hickory, NC
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PMG Research of Hickory, LLC
Hickory, North Carolina 28602
922
mi
from
Hickory, NC
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Catawba Valley Medical Group, Inc.
Hickory, North Carolina 28601
921
mi
from
Hickory, NC
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Gulf Coast Medical Research, LLC
Houston, Texas 77025
573
mi
from
Houston, TX
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Office of Michelle Zaniewski MD., PA.
Houston, Texas 77090
551
mi
from
Houston, TX
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Juno Research
Houston, Texas 77074
572
mi
from
Houston, TX
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Apex Cardiology
Jackson, Tennessee 38301
520
mi
from
Jackson, TN
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Research Associates of Jackson
Jackson, Tennessee 38301
519
mi
from
Jackson, TN
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Juno Research, LLC
Katy, Texas 77450
562
mi
from
Katy, TX
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Clinical Investigation Specialists
Kenosha, Wisconsin 53142
620
mi
from
Kenosha, WI
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PMG Research Inc. d/b/a PMG Research of Knoxville
Knoxville, Tennessee 37912
777
mi
from
Knoxville, TN
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Imperial Health, LLP
Lake Charles, Louisiana 70601
582
mi
from
Lake Charles, LA
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Lynn Institute of the Ozarks
Little Rock, Arkansas 72205
369
mi
from
Little Rock, AR
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The Office of Larry Watkins, MD
Little Rock, Arkansas 72205
368
mi
from
Little Rock, AR
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The American Institute of Research
Los Angeles, California 90017
1179
mi
from
Los Angeles, CA
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IMD Medical Group
Los Angeles, California 90020
1171
mi
from
Los Angeles, CA
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lntermed Group
Los Angeles, California 90017
1168
mi
from
Los Angeles, CA
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HFM Heart and Vascular Center/Holy Family Memorial, Inc
Manitowoc, Wisconsin 54220
687
mi
from
Manitowoc, WI
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Crescent City Clinical Research Center
Metairie, Louisiana 70006
693
mi
from
Metairie, LA
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Sunrise Research Institute, Inc
Miami, Florida 33130
1321
mi
from
Miami, FL
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Prestige Clinical Research Center Inc.
Miami, Florida 33125
1321
mi
from
Miami, FL
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Elite Clinical Research
Miami, Florida 33144
1316
mi
from
Miami, FL
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Columbus Clinical Services, LLC
Miami, Florida 33174
1321
mi
from
Miami, FL
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The Research Specialists of Florida, Inc.
Miami, Florida 33162
1314
mi
from
Miami, FL
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Advanced Clinical Research of Miami
Miami, Florida 33155
1317
mi
from
Miami, FL
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Suncoast Research Group, LLD
2128 West Flagler Street
Miami, Florida 33135
1319
mi
from
Miami, FL
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NewPhase Clinical Trials, Corp.
Miami Beach, Florida 33140
1321
mi
from
Miami Beach, FL
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Panax Clinical Research
Miami Lakes, Florida 33014
1309
mi
from
Miami Lakes, FL
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Precision Research Organization
Miami Lakes, Florida 33016
1309
mi
from
Miami Lakes, FL
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First Quality
Miramar, Florida 33025
1307
mi
from
Miramar, FL
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Gulf Coast Medical Research,LLC
Missouri City, Texas 77459
586
mi
from
Missouri City, TX
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Clinical Trials of America LA, LLC
Monroe, Louisiana 71203
484
mi
from
Monroe, LA
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National Clinical Research - Norfolk, Inc.
Norfolk, Virginia 23502
1186
mi
from
Norfolk, VA
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The Office of Lucita M. Cruz, M.D., Inc.
Norwalk, California 90650
1163
mi
from
Norwalk, CA
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American Family Medical
Ocala, Florida 34471
1080
mi
from
Ocala, FL
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South Oklahoma Heart Research
Oklahoma City, Oklahoma 73135
163
mi
from
Oklahoma City, OK
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Aspen Clinical Research, LLC
Orem, Utah 84058
764
mi
from
Orem, UT
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Pines Care Research Center, LLC
Pembroke Pines, Florida 33026
1305
mi
from
Pembroke Pines, FL
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DBC Research USA
Pembroke Pines, Florida 33029
1305
mi
from
Pembroke Pines, FL
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Andres Patron, D.O.P.A.
10796 Pines Boulevard
Pembroke Pines, Florida 33026
1306
mi
from
Pembroke Pines, FL
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The Office of Daniel G. Williams, MD
Perrysburg, Ohio 43551
798
mi
from
Perrysburg, OH
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Clinical Research Advantage, Inc./ Family Practice Specialists, Ltd.
Phoenix, Arizona 85018
845
mi
from
Phoenix, AZ
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Riser Medical Research
Picayune, Mississippi 39466
682
mi
from
Picayune, MS
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Clinical Research Advantage, Inc./ Plano Internal Medicine Associates
Plano, Texas 75093
332
mi
from
Plano, TX
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Progressive Medical Research
Port Orange, Florida 32127
1136
mi
from
Port Orange, FL
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Sound Health Care Center
Port Orchard, Washington 98366
1422
mi
from
Port Orchard, WA
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Sound Medical Research
Port Orchard, Washington 98366
1422
mi
from
Port Orchard, WA
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ActivMed Practices & Research, Inc.
Portsmouth, New Hampshire 03801
1463
mi
from
Portsmouth, NH
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Wake Research Associates, LLC
3100 Duraleigh Rd
Raleigh, North Carolina 27612
(919) 781-2514
Wake Research Associates, LLC Wake Research is an Organization of Unified Investigational Sites working closely...
1064
mi
from
Raleigh, NC
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Superior Research LLC
Sacramento, California 95825
1283
mi
from
Sacramento, CA
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East Coast Institute for RSCH, St. Augustine Cardiology Associates, Research
Saint Augustine, Florida 32086
1094
mi
from
Saint Augustine, FL
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East Coast Institute for Research, LLC/ Baker-Gilmour Cardiovascular Institute
Saint Augustine, Florida 32086
1089
mi
from
Saint Augustine, FL
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CentraCare Heart & Vascular Center @ St. Cloud Hospital
1406 6th Avenue North
Saint Cloud, Minnesota 56303
572
mi
from
Saint Cloud, MN
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Washington University Center for Advanced Medicine
4921 Parkview Place
Saint Louis, Missouri 63110
414
mi
from
Saint Louis, MO
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Washington University School of Medicine
660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
414
mi
from
Saint Louis, MO
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Meridien Research
Saint Petersburg, Florida 33709
1115
mi
from
Saint Petersburg, FL
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Radiant Research
Santa Rosa, California 95405
1348
mi
from
Santa Rosa, CA
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Cardiovascular Center of Sarasota
Sarasota, Florida 34239
1143
mi
from
Sarasota, FL
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Gulf Coast Medical Research, LLC
2225 Williams Trace Boulevard
Sugar Land, Texas 77478
577
mi
from
Sugar Land, TX
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Meridien Research
Tampa, Florida
1117
mi
from
Tampa, FL
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