Ombitasvir/ABT-450/Ritonavir and Dasabuvir With or Without Ribavirin in HCV Genotype 1-Infected Adults With Chronic Kidney Disease

Inclusion Criteria:

1. Positive for anti-HCV Ab (Antibody) and HCV RNA >1,000 IU/mL at Screening.

2. Screening laboratory result indicating HCV genotype 1 infection.

3. Subject has never received antiviral treatment for hepatitis C infection
(treatment-naive subject) or subject has received previous treatment with
peginterferon with or without RBV with non-response (HCV RNA quantifiable at end of
treatment or relapsed after end of treatment).

4. Estimated Glomerular Filtration Rate (eGFR) < 30 mL/min/1.73 m^2 as estimated by the
Modification of Diet in Renal Disease (MDRD) method.

Exclusion Criteria:

1. Women who are pregnant or breastfeeding.

2. Positive test result for Hepatitis B surface antigen (HBsAg) or anti-Human
Immunodeficiency Virus (HIV Ab).

3. Any current or past clinical evidence of Child-Pugh B or C classification or clinical
history of liver decompensation such as ascites (noted on physical exam), variceal
bleeding, or hepatic encephalopathy.