Use of Gadolinium in CT Pulmonary Angiography
| Status: | Not yet recruiting |
|---|---|
| Conditions: | Cardiology, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 20 - Any |
| Updated: | 4/2/2016 |
| Start Date: | April 2015 |
| End Date: | December 2019 |
Efficacy of Gadolinium Contrast in CT Pulmonary Angiography in Patients With Allergy to Iodine
The study will investigate patients with clinical suspicion for pulmonary embolism (PE) who
have a contraindication to iodine based contrast. These patients normally get investigated
with studies such as ultrasound and nuclear medicine studies but the fastest and preferred
investigation is CT with contrast to look for filling defects in the pulmonary arteries. The
investigators will assess whether gadolinium, which is currently used with MRI can be used
with CT as an alternative effective contrast in diagnosis or exclusion of PE. A new type of
CT scanner, a Dual Energy Scanner will be used to improve the visibility of Gadolinium
contrast on CT.
have a contraindication to iodine based contrast. These patients normally get investigated
with studies such as ultrasound and nuclear medicine studies but the fastest and preferred
investigation is CT with contrast to look for filling defects in the pulmonary arteries. The
investigators will assess whether gadolinium, which is currently used with MRI can be used
with CT as an alternative effective contrast in diagnosis or exclusion of PE. A new type of
CT scanner, a Dual Energy Scanner will be used to improve the visibility of Gadolinium
contrast on CT.
Contrast enhancement with Gadolinium will be evaluated to assess its efficacy for diagnosis
and exclusion of pulmonary embolism in a patient who previously would not have been
investigated with CTPA due to an underlying allergy to contrast or other contraindication.
If this proves beneficial, it will allow such patients to be investigated successfully with
CTPA
and exclusion of pulmonary embolism in a patient who previously would not have been
investigated with CTPA due to an underlying allergy to contrast or other contraindication.
If this proves beneficial, it will allow such patients to be investigated successfully with
CTPA
Inclusion Criteria:
- Patients suspected of having a Pulmonary embolus
- Allergy to Iodine based intravenous contrast
Exclusion Criteria:
- Renal impairment
- Less than 20 years of age
- Non-English speaking
- Pregnancy
- Allergy to Gadolinium
We found this trial at
1
site
Click here to add this to my saved trials
