The Aerobic & Cognitive Exercise Study
| Status: | Completed |
|---|---|
| Conditions: | Cognitive Studies, Healthy Studies |
| Therapuetic Areas: | Psychiatry / Psychology, Other |
| Healthy: | No |
| Age Range: | 50 - Any |
| Updated: | 5/5/2018 |
| Start Date: | September 2014 |
| End Date: | July 2017 |
The Cognitive Benefits of Interactive Mental and Physical Exercise for Older Adults at Risk for or With Mild Cognitive Impairment (MCI)
The purpose of this study is to clarify the benefits to brain health and thinking processes
that result from different forms of exercise. This study will examine the effectiveness of
cybercycling (virtual reality enhanced stationary cycling) for persons at risk for and with
MCI, and compare this with the individual cognitive, behavioral, and physiological effects of
physical and mental exercise alone. The Investigators hypothesis that cognitive benefit will
be greatest for combined aerobic and cognitive exercise compared to physical and mental
exercise alone.
that result from different forms of exercise. This study will examine the effectiveness of
cybercycling (virtual reality enhanced stationary cycling) for persons at risk for and with
MCI, and compare this with the individual cognitive, behavioral, and physiological effects of
physical and mental exercise alone. The Investigators hypothesis that cognitive benefit will
be greatest for combined aerobic and cognitive exercise compared to physical and mental
exercise alone.
This is a multi-site, randomized controlled trial. Participants will be randomized into one
of three conditions for six months: cybercycle-tour, cybercycle-game, or videogame alone.
Comprehensive evaluations will include: neuropsychological (e.g., executive function and
memory), behavioral (e.g., compliance and effort/watts), physiological (e.g.,
cardiorespiratory fitness), biomarker (e.g., BDNF), and an expanded neuroimaging pilot. After
the six-month intervention period, participants choose whether or not to continue exercising,
using any of the three conditions.
of three conditions for six months: cybercycle-tour, cybercycle-game, or videogame alone.
Comprehensive evaluations will include: neuropsychological (e.g., executive function and
memory), behavioral (e.g., compliance and effort/watts), physiological (e.g.,
cardiorespiratory fitness), biomarker (e.g., BDNF), and an expanded neuroimaging pilot. After
the six-month intervention period, participants choose whether or not to continue exercising,
using any of the three conditions.
Inclusion Criteria:
- age 50+
- able to pedal recumbent stationary bicycle
- available for regular exercise participation 3-5x/week for at least 6 months
- physician permission to exercise
Exclusion Criteria:
- unstable heart condition or other significant cardiovascular history (e.g,. stroke)
- meets criteria for Alzheimer's or other dementia
- significant history of other neurological disease (e.g., seizures, Parkinson's, etc.)
- physician denial to exercise
We found this trial at
12
sites
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