An Exercise Intervention for Prostate Cancer Patients Receiving Androgen Deprivation Therapy

This study will assess the feasibility of an exercise intervention to counteract adverse side
effects related to ADT in prostate cancer (PCa) patients. Specifically, we will use an
exercise intervention and assess its impact on bone mass density, Body Mass Index (BMI),
hip/waist circumference levels, biomarkers (i.e., glucose, lipids), step count, grip
strength, and health-related quality of life (HRQOL) using the Patient Reported Outcomes
Measurement Information System (PROMIS®). In this 8-week two-arm randomized clinical trial,
40 PCa patients receiving ADT will be randomly assigned to an exercise (n=20) or a stretching
control group (n=20) with a follow-up at 8-weeks.

Inclusion Criteria:

- (1) Caucasian or African-American/Black men; (2) histologically confirmed
non-metastatic PCa; (3) receiving ADT treatment for 9-months or less upon recruitment
(and continue to receive treatment during the duration of the study); (4) 40 to 75
years old; (5) sedentary defined as <60 minutes of recreation or work requiring modest
PA/week; (6) ability to perform the level of physical activity assessed by the
Physical Activity Readiness Questionnaire (PAR-Q); (6) has access to a smartphone or
computer with internet capabilities

Exclusion Criteria:

- (1) severe cardiac disease; (2) recent myocardial infarction; (3) treated for any
other cancer; (4) any physical, psychological illness, and/or medical problems that
restricted them from exercise; (5) and not willing or able to follow procedures
specified by the study and/or instructions of the researcher.